Peptic ulcer disease and non-steroidal anti-inflammatory drugs

Non-steroidal anti-inflammatory drugs including low-dose aspirin are some of the most commonly used medicines. They are associated with gastrointestinal mucosal injury. Before prescribing, it is important to assess the patient’s gastrointestinal risk factors such as age and history of peptic ulcers....

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Bibliographic Details
Published in:Australian prescriber 2017-06, Vol.40 (3), p.91-93
Main Author: Drini, Musa
Format: Article
Language:English
Subjects:
Anti-inflammatory agents
Anticoagulants
Aspirin
Biosynthesis
Data analysis
Disease prevention
Drug dosages
Nonsteroidal anti-inflammatory drugs
Prescription drugs
Protons
Risk factors
Steroids
Ulcers
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Description
Summary:Non-steroidal anti-inflammatory drugs including low-dose aspirin are some of the most commonly used medicines. They are associated with gastrointestinal mucosal injury. Before prescribing, it is important to assess the patient’s gastrointestinal risk factors such as age and history of peptic ulcers. Patients at high risk may require co-prescription to reduce the risk of peptic ulcers. A daily dose of a proton pump inhibitor is the most effective method of reducing the risk of ulcers induced by non-steroidal anti-inflammatory drugs.
ISSN:0312-8008
1839-3942
DOI:10.18773/austprescr.2017.037