Maternal and pregnancy-related factors affecting human milk cytokines among Peruvian mothers bearing low-birth-weight neonates

Highlights • A core of 12 cytokines is detected in human milk across different lactation stages. • Specific pregnancy complications are associated with distinct breast milk cytokine signatures. • Mothers of very small neonates have higher concentrations of many cytokines in their breast milk

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Bibliographic Details
Published in:Journal of reproductive immunology 2017-04, Vol.120, p.20-26
Main Authors: Zambruni, Mara, Villalobos, Alex, Somasunderam, Anoma, Westergaard, Sarah, Nigalye, Maitreyee, Turin, Christie G, Zegarra, Jaime, Bellomo, Sicilia, Mercado, Erik, Ochoa, Theresa J, Utay, Netanya S
Format: Article
Language:English
Subjects:
Adult
Cohort Studies
Cytokines - metabolism
Female
Human milk cytokines
Humans
Immunity, Innate
Infant, Low Birth Weight
Infant, Newborn
Lactation - immunology
Low-birth weight infants
Maternal Age
Milk, Human - metabolism
Obstetrics and Gynecology
Peru
Pregnancy
Pregnancy complications
Pregnancy Complications, Cardiovascular - epidemiology
Pregnancy Complications, Cardiovascular - immunology
Premature Birth - epidemiology
Premature Birth - immunology
Risk Factors
Transcriptome
Young Adult
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Description
Summary:Highlights • A core of 12 cytokines is detected in human milk across different lactation stages. • Specific pregnancy complications are associated with distinct breast milk cytokine signatures. • Mothers of very small neonates have higher concentrations of many cytokines in their breast milk
ISSN:0165-0378
1872-7603
1872-7603
DOI:10.1016/j.jri.2017.04.001