Comparison of Effort of Breathing for Infants on Nasal Modes of Respiratory Support

Objective To directly compare effort of breathing between high flow nasal cannula (HFNC), nasal intermittent mechanical ventilation (NIMV), and nasal continuous positive airway pressure (NCPAP). Study design This was a single center prospective cross-over study for patients 60%), PRP on NIMV was low...

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Bibliographic Details
Published in:The Journal of pediatrics 2017-06, Vol.185, p.26-32.e3
Main Authors: Kamerkar, Asavari, DO, Hotz, Justin, RRT, Morzov, Rica, RN, Newth, Christopher J.L., MD, Ross, Patrick A., MD, Khemani, Robinder G., MD, MsCI
Format: Article
Language:English
Subjects:
Airway Extubation
Cannula
Continuous Positive Airway Pressure
Cross-Over Studies
Esophagus
Female
Heart Defects, Congenital - surgery
Humans
humidified high flow nasal cannula
Infant
Infant, Newborn
Intensive Care Units, Pediatric
Intermittent Positive-Pressure Ventilation
Male
Manometry
nasal continuous positive airway pressure
nasal intermittent mechanical ventilation
Oxygen Inhalation Therapy - methods
Pediatrics
Postoperative Care
Prospective Studies
Respiratory Insufficiency - therapy
Spirometry
Work of Breathing
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Summary:Objective To directly compare effort of breathing between high flow nasal cannula (HFNC), nasal intermittent mechanical ventilation (NIMV), and nasal continuous positive airway pressure (NCPAP). Study design This was a single center prospective cross-over study for patients 60%), PRP on NIMV was lower than on HFNC. Conclusions For infants, effort of breathing is similar on HFNC, NIMV, and NCPAP after extubation, regardless of flow rate or inspiratory pressure. We speculate that bi-level NIMV may be superior if high levels of synchrony can be achieved.
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2017.02.060