Alcohol Intake and Breast Cancer Risk in African American Women from the AMBER Consortium

• Published in: Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2017-05, Vol.26 (5), p.787-794
• Main Authors: Williams, Lindsay A, Olshan, Andrew F, Hong, Chi-Chen, Bandera, Elisa V, Rosenberg, Lynn, Cheng, Ting-Yuan David, Lunetta, Kathryn L, McCann, Susan E, Poole, Charles, Kolonel, Laurence N, Palmer, Julie R, Ambrosone, Christine B, Troester, Melissa A
• Format: Article
• Language: English
• Subjects: Adult; African Americans; Age; Aged; Alcohol Drinking - adverse effects; Alcohol Drinking - epidemiology; Alcoholic beverages; Alcohols; Amber; Black or African American; Breast cancer; Breast Neoplasms - epidemiology; Consortia; Drinking behavior; Epidemiology; ErbB-2 protein; Female; Health risk assessment; Health risks; Humans; Invasiveness; Middle Aged; Odds Ratio; Risk factors; Sensitivity analysis; Smoking; United States - epidemiology; Young Adult
• ISSN: 1055-9965; 1538-7755
• DOI: 10.1158/1055-9965.EPI-16-0792

Alcohol is a recognized risk factor for invasive breast cancer, but few studies involve African American women. The current analysis included 22,338 women (5,108 cases of invasive breast cancer) from the African American Breast Cancer Epidemiology and Risk (AMBER) Consortium. The association between number of alcoholic drinks per week (dpw) and breast cancer was estimated using logistic regression, adjusting for potential confounders, and stratifying by breast cancer subtype. Approximately 35% of controls were current drinkers at interview. Women who reported current drinking of ≥14 dpw had an elevated risk of breast cancer compared with light drinkers (>0-