Affective dysregulation predicts incident nonmedical prescription analgesic use among college students

• Published in: Addictive behaviors 2018-01, Vol.76, p.328-334
• Main Authors: Morioka, Christine K., Howard, Donna E., Caldeira, Kimberly M., Wang, Min Qi, Arria, Amelia M.
• Format: Article
• Language: English
• Subjects: Adult; Affective dysregulation; Analgesics; Children; College students; Colleges & universities; Comorbidity; Demographics; Drug abuse; Drug use; Emotional disorders; Emotional regulation; Female; Humans; Intervention; Longitudinal Studies; Male; Mental depression; Mid-Atlantic Region - epidemiology; Minority & ethnic groups; Mood Disorders - epidemiology; Mood Disorders - psychology; Nonmedical use; Opiates; Prescription Drug Misuse - psychology; Prescription Drug Misuse - statistics & numerical data; Prescription opioids; Prospective Studies; Risk Factors; Students - psychology; Students - statistics & numerical data; Substance-Related Disorders - epidemiology; Substance-Related Disorders - psychology; Universities; Young Adult
• ISSN: 0306-4603; 1873-6327
• DOI: 10.1016/j.addbeh.2017.08.034

This study investigated the relationship between four suspected risk factors—affective dysregulation, conduct problems, depressive symptoms, and psychological distress—and incident nonmedical prescription analgesic (NPA) use among college students. The sample was derived from 929 college students from a large, mid-Atlantic university who completed the third annual College Life Study assessment (Y3) and were NPA use naïve at baseline (Y1). A series of logistic regression analyses were conducted to evaluate the predictors of incident NPA use by Y3. Separate models were developed to evaluate the association between the suspected risk factors and (a) NPA use relative to non-use of other drugs, including nonmedical use of other drug classes, (b) NPA use relative to other drug use, and (c) other drug use relative to non-use. All models included gender, parental education level, and race/ethnicity. Affective dysregulation was significantly associated with becoming an incident NPA user relative to both drug users without NPA use as well as non-users, after statistically controlling for demographic characteristics and other factors. Conduct problems in early childhood were positively related to both incident NPA use and other drug use without NPA use relative to non-users, after statistically controlling for demographic characteristics and other factors. Depressive symptoms were associated with NPA incidence at the bivariate level only. These findings extend previous research suggesting that NPA use might be related to deficits in regulating negative emotional states, and highlight possible markers for screening and intervention to prevent NPA use. •Affective dysregulation predicted incident nonmedical prescription analgesic use•Conduct problems predicted nonmedical prescription analgesic and other drug use•Possible markers for screening and intervention to prevent NPA use are discussed