Treatment of acne scarring with a novel fractionated, dual‐wavelength, picosecond‐domain laser incorporating a novel holographic beam‐splitter

• Published in: Lasers in surgery and medicine 2017-11, Vol.49 (9), p.796-802
• Main Authors: Bernstein, Eric F., Schomacker, Kevin T., Basilavecchio, Lisa D., Plugis, Jessica M., Bhawalkar, Jayant D.
• Format: Article
• Language: English
• Subjects: Acne; acne scars; Acne Vulgaris - complications; Acne Vulgaris - pathology; Acne Vulgaris - therapy; Adult; Aged; Cicatrix - etiology; Cicatrix - pathology; Cicatrix - therapy; Clinical Reports; Digital imaging; Discomfort; Edema; Editor's Choice; Erythema; Female; Follow-Up Studies; fractionated; Humans; laser; Laser beams; Lasers; Lasers, Solid-State - therapeutic use; Low-Level Light Therapy - instrumentation; Low-Level Light Therapy - methods; Male; Middle Aged; Patient Satisfaction; picosecond; Prospective Studies; Purpura; Scars; Self-assessment; Side effects; Splitting; Surgery; treatment; Treatment Outcome; Wavelength; Young Adult
• ISSN: 0196-8092; 1096-9101
• DOI: 10.1002/lsm.22734

Background and Objectives Fractional treatment with a dual wavelength 1,064 and 532 nm picosecond‐domain laser, delivering a 10 × 10 array of highly focused beamlets via a holographic optic, was investigated for the treatment of acne scars. Study Twenty‐seven of 31 subjects completed the study, 19 were treated using 1,064 nm and 8 were treated at 532 nm, all having four‐monthly treatments. Blinded evaluation of digital images by three physician evaluators comparing pre‐ and 3‐month post‐treatment images measured efficacy using a 10‐point scale. Subject self‐assessment of treatment effects were also recorded. Safety was measured by recording subject discomfort scores and adverse effects. Results Blinded reviewers correctly identified the baseline image in 61 of the 81 image sets (75%), and baseline acne scar scores were 1.8 ± 0.7 and 1.8 ± 0.5 for the 1,064 and 532 nm cohorts, and decreased to 1.1 ± 0.5 (P