Cutaneous lymphoid hyperplasia (pseudolymphoma)

Zhou and Mistry provide details on a 48-year-old otherwise healthy woman presented to the dermatology clinic with a six-week history of a red lesion on the right cheek. The lesion was generally asymptomatic, although the patient reported some occasional itch and tenderness. The referring primary car...

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Bibliographic Details
Published in:Canadian Medical Association journal (CMAJ) 2018-04, Vol.190 (13), p.E398-E398
Main Authors: Zhou, Linghong Linda, BHSc, Mistry, Nisha, MD
Format: Article
Language:English
Subjects:
Administration, Topical
Antibiotics
Biopsy
Case reports
Cheek
Dermatology
Diagnosis
Dosage and administration
Doxycycline
Drug therapy
Face
Female
Health aspects
Humans
Hyperplasia
Internal Medicine
Lymphoma
Lymphomas
Medical diagnosis
Medical procedures
Middle Aged
Patients
Practice
Pseudolymphoma - diagnosis
Pseudolymphoma - drug therapy
Pseudolymphoma - pathology
Skin Diseases - diagnosis
Skin Diseases - drug therapy
Skin Diseases - pathology
Steroids - administration & dosage
Women
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Description
Summary:Zhou and Mistry provide details on a 48-year-old otherwise healthy woman presented to the dermatology clinic with a six-week history of a red lesion on the right cheek. The lesion was generally asymptomatic, although the patient reported some occasional itch and tenderness. The referring primary care provider had made a presumptive diagnosis of acne cyst and prescribed treatment with doxycycline (100 mg administered orally and taken daily for 30 days), but there was no substantial change. Results from immunohistochemistry testing showed a mixed population of B and T cells. Based on these features, we diagnosed cutaneous lymphoid hyperplasia (pseudolymphoma). Pseudolymphoma is a benign inflammatory response occasionally linked to an inciting antigen that simulates cutaneous lymphomas. The clinical presentation is a skin-colored or red nodule on the face or chest, although multiple or generalized lesions can also be seen.
ISSN:0820-3946
1488-2329
DOI:10.1503/cmaj.170812