The effect of the type of dietary protein on the development of ovarian cancer

We evaluated whether different dietary protein qualities (isocaloric diets involving animal (casein) or plant protein (soy protein) could inhibit the ovarian cancer growth in mice and improve their prognosis and whether chemotherapy had different tumor reducing effects on these mice. In the mice of...

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Bibliographic Details
Published in:Oncotarget 2018-05, Vol.9 (35), p.23987-23999
Main Authors: Taha, Ahmed A A, Koshiyama, Masafumi, Matsumura, Noriomi, Abiko, Kaoru, Yamaguchi, Ken, Hamanishi, Jyunzo, Baba, Tsukasa, Kharma, Budiman, Mohamed, Ibrahim Hassanin, Ameen, Magdy Mohamed, Ismail, Salah Ali, Konishi, Ikuo, Mandai, Masaki
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Language:English
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Research Paper
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Summary:We evaluated whether different dietary protein qualities (isocaloric diets involving animal (casein) or plant protein (soy protein) could inhibit the ovarian cancer growth in mice and improve their prognosis and whether chemotherapy had different tumor reducing effects on these mice. In the mice of the 20% plant protein group, the ovarian cancer growth at 5 weeks after tumor implantation was clearly reduced in comparison to the mice in the 20% animal protein group (p< 0.001). The serum levels of insulin and IGF-1 levels were both lower in the mice of the 20% plant protein group than in the mice of the 20% animal protein group (p
ISSN:1949-2553
1949-2553
DOI:10.18632/oncotarget.25253