Coffee and tea drinking in relation to risk of hip fracture in the Singapore Chinese Health Study

Meta-analyses of studies conducted among Western populations suggest that coffee consumption does not affect osteoporotic fracture risk. However, experimental studies have shown that the effect of caffeine on bone health may depend on dosage. We examined the associations between consumption of coffe...

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Bibliographic Details
Published in:Bone (New York, N.Y.) N.Y.), 2018-07, Vol.112, p.51-57
Main Authors: Dai, Zhaoli, Jin, Aizhen, Soh, Avril Zixin, Ang, Li-Wei, Yuan, Jian-Min, Koh, Woon-Puay
Format: Article
Language:English
Subjects:
Aged
Asian Continental Ancestry Group
Beverages - adverse effects
Caffeine
Chinese
Coffee
Coffee - adverse effects
Female
Health
Hip fracture
Hip Fractures - epidemiology
Humans
Male
Middle Aged
Postmenopause
Risk Factors
Singapore
Tea
Tea - adverse effects
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Summary:Meta-analyses of studies conducted among Western populations suggest that coffee consumption does not affect osteoporotic fracture risk. However, experimental studies have shown that the effect of caffeine on bone health may depend on dosage. We examined the associations between consumption of coffee, tea and caffeine and risk of hip fracture in an Asian cohort. In a population-based prospective cohort of 63,257 Chinese men and women aged 45–74 years in Singapore, a validated semi-quantitative food frequency questionnaire was used to assess habitual consumption of coffee and tea at baseline. Cox proportional hazards regression models were used to estimate hazard ratio (HR) and 95% confidence interval (CI) for risk of hip fracture with adjustment for potential confounders. During a mean follow-up of 16.7 years, 2502 incident hip fracture cases were identified. Compared to coffee drinkers
ISSN:8756-3282
1873-2763
DOI:10.1016/j.bone.2018.04.010