The Factors Affecting the Non-dipper Pattern in Japanese Patients with Severe Obstructive Sleep Apnea

Objective Obstructive sleep apnea (OSA) is assumed to influence the circadian blood pressure (BP) fluctuation, particularly causing nocturnal hypertension and changing the dipping pattern of nocturnal BP. This study aimed to clarify the triggers of the non-dipper pattern in nocturnal BP in Japanese...

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Bibliographic Details
Published in:Internal Medicine 2018/06/01, Vol.57(11), pp.1553-1559
Main Authors: Sekizuka, Hiromitsu, Osada, Naohiko, Akashi, Yoshihiro J
Format: Article
Language:English
Subjects:
ambulatory blood pressure monitoring
Angiotensin
Angiotensin II
Angiotensin-converting enzyme inhibitors
Apnea
Blood pressure
circadian rhythm
Circadian rhythms
Dependent variables
Desaturation
Enzyme inhibitors
Health risk assessment
Internal medicine
Multivariate analysis
nocturnal blood pressure
Original
Peptidyl-dipeptidase A
polysomnography
Regression analysis
Risk factors
Sleep
Sleep apnea
Sleep disorders
sleep-disordered breathing
Variation
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Summary:Objective Obstructive sleep apnea (OSA) is assumed to influence the circadian blood pressure (BP) fluctuation, particularly causing nocturnal hypertension and changing the dipping pattern of nocturnal BP. This study aimed to clarify the triggers of the non-dipper pattern in nocturnal BP in Japanese patients with severe OSA (the apnea-hypopnea index ≥30/h). Methods Of 541 patients with OSA diagnosed using polysomnography (PSG) and ambulatory BP monitoring (ABPM), 163 patients
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.0029-17