Serum Lipid Profile and Its Association with Diabetes and Prediabetes in a Rural Bangladeshi Population

• Published in: International journal of environmental research and public health 2018-09, Vol.15 (9), p.1944
• Main Authors: Bhowmik, Bishwajit, Siddiquee, Tasnima, Mujumder, Anindita, Afsana, Faria, Ahmed, Tareen, Mdala, Ibrahimu A, do V Moreira, Nayla Cristina, Khan, Abul Kalam Azad, Hussain, Akhtar, Holmboe-Ottesen, Gerd, Omsland, Tone Kristin
• Format: Article
• Language: English
• Subjects: Adult; Adults; Anthropometry; Asian People; Bangladesh - epidemiology; Blood Glucose; Blood pressure; Cardiovascular disease; Cholesterol; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Covariance; Cross-Sectional Studies; Diabetes Mellitus; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - epidemiology; Dyslipidemia; Dyslipidemias - blood; Dyslipidemias - complications; Dyslipidemias - epidemiology; Fasting; Female; Glucose; Glucose tolerance; Glucose Tolerance Test; High density lipoprotein; Humans; Intolerance; Lipids; Lipids - blood; Low density lipoprotein; Male; Middle Aged; Odds Ratio; Prediabetic State - blood; Prediabetic State - complications; Prediabetic State - epidemiology; Prevalence; Regression analysis; Rural Population; Serum lipids; Studies; Triglycerides; Triglycerides - blood; Womens health
• ISSN: 1660-4601; 1661-7827; 1660-4601
• DOI: 10.3390/ijerph15091944

Dyslipidemia is commonly associated with diabetes (T2DM). This has been demonstrated for the Caucasian population, but few data are available for Asian Indians. The paper aims to investigate serum lipids (separately or in combination) and their association with glucose intolerance status (T2DM and prediabetes) in a rural Bangladeshi population. A sample of 2293 adults (≥20 years) were included in a community based cross-sectional survey in 2009. Anthropometric measures, blood pressure, blood glucose (fasting and 2-h oral glucose tolerance test) and fasting serum lipids (total cholesterol, T-Chol; triglycerides, Tg; low density lipoprotein cholesterol, LDL-C and high density lipoprotein cholesterol, HDL-C) were registered. Analysis of covariance (ANCOVA) and regression analysis were performed. High Tg levels were seen in 26% to 64% of the participants, depending on glucose tolerance status. Low HDL-C levels were seen in all groups (>90%). Significant linear trends were observed for high T-Chol, high Tg and low HDL-C with increasing glucose intolerance ( for trend