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Intellectual engagement and cognitive ability in later life (the “use it or lose it” conjecture): longitudinal, prospective study

AbstractObjectivesTo examine the association between intellectual engagement and cognitive ability in later life, and determine whether the maintenance of intellectual engagement will offset age related cognitive decline.DesignLongitudinal, prospective, observational study.SettingNon-clinical volunt...

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Bibliographic Details
Published in:BMJ (Online) 2018-12, Vol.363, p.k4925-k4925
Main Authors: Staff, Roger T, Hogan, Michael J, Williams, Daniel S, Whalley, L J
Format: Article
Language:English
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Summary:AbstractObjectivesTo examine the association between intellectual engagement and cognitive ability in later life, and determine whether the maintenance of intellectual engagement will offset age related cognitive decline.DesignLongitudinal, prospective, observational study.SettingNon-clinical volunteers in late middle age (all born in 1936) living independently in northeast Scotland.ParticipantsSample of 498 volunteers who had taken part in the Scottish Mental Health Survey of 1947, from one birth year (1936).Main outcome measuresCognitive ability and trajectory of cognitive decline in later life. Typical intellectual engagement was measured by a questionnaire, and repeated cognitive measurements of information processing speed and verbal memory were obtained over a 15 year period (recording more than 1200 longitudinal data points for each cognitive test).ResultsIntellectual engagement was significantly associated with level of cognitive performance in later life, with each point on a 24 point scale accounting for 0.97 standardised cognitive performance (IQ-like) score, for processing speed and 0.71 points for memory (both P
ISSN:0959-8138
1756-1833
DOI:10.1136/bmj.k4925