Loading…
Genomic Features, Comparative Genomics, and Antimicrobial Susceptibility Patterns of Elizabethkingia bruuniana
Elizabethkingia bruuniana is a novel species of the Elizabethkingia genus. There is scant information on this microorganism. Here, we report the whole-genome features and antimicrobial susceptibility patterns of E . bruuniana strain EM798-26. Elizabethkingia strain EM798-26 was initially identified...
Saved in:
Published in: | Scientific reports 2019-02, Vol.9 (1), p.2267-2267, Article 2267 |
---|---|
Main Authors: | , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c511t-6b612476828caaa8635253a01411ed4066cd04b17f127ff501dc3844477ff61f3 |
---|---|
cites | cdi_FETCH-LOGICAL-c511t-6b612476828caaa8635253a01411ed4066cd04b17f127ff501dc3844477ff61f3 |
container_end_page | 2267 |
container_issue | 1 |
container_start_page | 2267 |
container_title | Scientific reports |
container_volume | 9 |
creator | Lin, Jiun-Nong Lai, Chung-Hsu Yang, Chih-Hui Huang, Yi-Han Lin, Hsi-Hsun |
description | Elizabethkingia bruuniana
is a novel species of the
Elizabethkingia
genus. There is scant information on this microorganism. Here, we report the whole-genome features and antimicrobial susceptibility patterns of
E
.
bruuniana
strain EM798-26.
Elizabethkingia
strain EM798-26 was initially identified as
E
.
miricola
. This isolate contained a circular genome of 4,393,011 bp. The whole-genome sequence-based phylogeny revealed that
Elizabethkingia
strain EM798-26 was in the same group of the type strain
E
.
bruuniana
G0146
T
. Both
in silico
DNA-DNA hybridization and average nucleotide identity analysis clearly demonstrated that
Elizabethkingia
strain EM798-26 was a species of
E
.
bruuniana
. The pan-genome analysis identified 2,875 gene families in the core genome and 5,199 gene families in the pan genome of eight publicly available
E
.
bruuniana
genome sequences. The unique genes accounted for 0.2–12.1% of the pan genome in each
E
.
bruuniana
. A total of 59 potential virulence factor homologs were predicted in the whole-genome of
E
.
bruuniana
strain EM798–26. This isolate was nonsusceptible to multiple antibiotics, but susceptible to aminoglycosides, minocycline, and levofloxacin. The whole-genome sequence analysis of
E
.
bruuniana
EM798-26 revealed 29 homologs of antibiotic resistance-related genes. This study presents the genomic features of
E
.
bruuniana
. Knowledge of the genomic characteristics provides valuable insights into a novel species. |
doi_str_mv | 10.1038/s41598-019-38998-6 |
format | article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6381114</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2183695403</sourcerecordid><originalsourceid>FETCH-LOGICAL-c511t-6b612476828caaa8635253a01411ed4066cd04b17f127ff501dc3844477ff61f3</originalsourceid><addsrcrecordid>eNp9kUFvFSEQx4mxsc2zX8CDIfHiwVUGWJa9mDQvbTVpYpPqmczusq_UXXgC26R-emnfs1YPcmGG-fFnhj8hr4C9Byb0hyShbnXFoK2EbkuknpEjzmRdccH58yfxITlO6YaVVfNWQvuCHArWaAFtc0T8ufVhdj09s5iXaNM7ug7zFiNmd2vpvlpO0Q_0xGdXshg6hxO9WlJvt9l1bnL5jl5izjb6RMNITyf3Ezubr787v3FIu7gs3qHHl-RgxCnZ4_2-It_OTr-uP1UXX84_r08uqr4GyJXqFHDZKM11j4haiZrXAhlIADtIplQ_MNlBMwJvxrFmMPRCSymbkikYxYp83Olul262Q299jjiZbXQzxjsT0Jm_K95dm024NUpoAJBF4O1eIIYfi03ZzK6MO03obViS4aBl6UZxVtA3_6A3YYm-jHdPCdXWkolC8R1Vvi-laMfHZoCZe0fNzlFTHDUPjpZeVuT10zEer_z2rwBiB6RS8hsb_7z9H9lfLp6tFg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2183695403</pqid></control><display><type>article</type><title>Genomic Features, Comparative Genomics, and Antimicrobial Susceptibility Patterns of Elizabethkingia bruuniana</title><source>Open Access: PubMed Central</source><source>Publicly Available Content (ProQuest)</source><source>Free Full-Text Journals in Chemistry</source><source>Springer Nature - nature.com Journals - Fully Open Access</source><creator>Lin, Jiun-Nong ; Lai, Chung-Hsu ; Yang, Chih-Hui ; Huang, Yi-Han ; Lin, Hsi-Hsun</creator><creatorcontrib>Lin, Jiun-Nong ; Lai, Chung-Hsu ; Yang, Chih-Hui ; Huang, Yi-Han ; Lin, Hsi-Hsun</creatorcontrib><description>Elizabethkingia bruuniana
is a novel species of the
Elizabethkingia
genus. There is scant information on this microorganism. Here, we report the whole-genome features and antimicrobial susceptibility patterns of
E
.
bruuniana
strain EM798-26.
Elizabethkingia
strain EM798-26 was initially identified as
E
.
miricola
. This isolate contained a circular genome of 4,393,011 bp. The whole-genome sequence-based phylogeny revealed that
Elizabethkingia
strain EM798-26 was in the same group of the type strain
E
.
bruuniana
G0146
T
. Both
in silico
DNA-DNA hybridization and average nucleotide identity analysis clearly demonstrated that
Elizabethkingia
strain EM798-26 was a species of
E
.
bruuniana
. The pan-genome analysis identified 2,875 gene families in the core genome and 5,199 gene families in the pan genome of eight publicly available
E
.
bruuniana
genome sequences. The unique genes accounted for 0.2–12.1% of the pan genome in each
E
.
bruuniana
. A total of 59 potential virulence factor homologs were predicted in the whole-genome of
E
.
bruuniana
strain EM798–26. This isolate was nonsusceptible to multiple antibiotics, but susceptible to aminoglycosides, minocycline, and levofloxacin. The whole-genome sequence analysis of
E
.
bruuniana
EM798-26 revealed 29 homologs of antibiotic resistance-related genes. This study presents the genomic features of
E
.
bruuniana
. Knowledge of the genomic characteristics provides valuable insights into a novel species.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-019-38998-6</identifier><identifier>PMID: 30783197</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>45 ; 631/326/1320 ; 631/326/325/1506 ; Antibiotic resistance ; Antibiotics ; Antimicrobial agents ; Deoxyribonucleic acid ; DNA ; Gene families ; Genes ; Genomes ; Genomics ; Humanities and Social Sciences ; Hybridization ; Levofloxacin ; Minocycline ; multidisciplinary ; Nucleotide sequence ; Phylogeny ; Science ; Science (multidisciplinary) ; Species ; Virulence factors</subject><ispartof>Scientific reports, 2019-02, Vol.9 (1), p.2267-2267, Article 2267</ispartof><rights>The Author(s) 2019</rights><rights>This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c511t-6b612476828caaa8635253a01411ed4066cd04b17f127ff501dc3844477ff61f3</citedby><cites>FETCH-LOGICAL-c511t-6b612476828caaa8635253a01411ed4066cd04b17f127ff501dc3844477ff61f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2183695403/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2183695403?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30783197$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lin, Jiun-Nong</creatorcontrib><creatorcontrib>Lai, Chung-Hsu</creatorcontrib><creatorcontrib>Yang, Chih-Hui</creatorcontrib><creatorcontrib>Huang, Yi-Han</creatorcontrib><creatorcontrib>Lin, Hsi-Hsun</creatorcontrib><title>Genomic Features, Comparative Genomics, and Antimicrobial Susceptibility Patterns of Elizabethkingia bruuniana</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>Elizabethkingia bruuniana
is a novel species of the
Elizabethkingia
genus. There is scant information on this microorganism. Here, we report the whole-genome features and antimicrobial susceptibility patterns of
E
.
bruuniana
strain EM798-26.
Elizabethkingia
strain EM798-26 was initially identified as
E
.
miricola
. This isolate contained a circular genome of 4,393,011 bp. The whole-genome sequence-based phylogeny revealed that
Elizabethkingia
strain EM798-26 was in the same group of the type strain
E
.
bruuniana
G0146
T
. Both
in silico
DNA-DNA hybridization and average nucleotide identity analysis clearly demonstrated that
Elizabethkingia
strain EM798-26 was a species of
E
.
bruuniana
. The pan-genome analysis identified 2,875 gene families in the core genome and 5,199 gene families in the pan genome of eight publicly available
E
.
bruuniana
genome sequences. The unique genes accounted for 0.2–12.1% of the pan genome in each
E
.
bruuniana
. A total of 59 potential virulence factor homologs were predicted in the whole-genome of
E
.
bruuniana
strain EM798–26. This isolate was nonsusceptible to multiple antibiotics, but susceptible to aminoglycosides, minocycline, and levofloxacin. The whole-genome sequence analysis of
E
.
bruuniana
EM798-26 revealed 29 homologs of antibiotic resistance-related genes. This study presents the genomic features of
E
.
bruuniana
. Knowledge of the genomic characteristics provides valuable insights into a novel species.</description><subject>45</subject><subject>631/326/1320</subject><subject>631/326/325/1506</subject><subject>Antibiotic resistance</subject><subject>Antibiotics</subject><subject>Antimicrobial agents</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>Gene families</subject><subject>Genes</subject><subject>Genomes</subject><subject>Genomics</subject><subject>Humanities and Social Sciences</subject><subject>Hybridization</subject><subject>Levofloxacin</subject><subject>Minocycline</subject><subject>multidisciplinary</subject><subject>Nucleotide sequence</subject><subject>Phylogeny</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Species</subject><subject>Virulence factors</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNp9kUFvFSEQx4mxsc2zX8CDIfHiwVUGWJa9mDQvbTVpYpPqmczusq_UXXgC26R-emnfs1YPcmGG-fFnhj8hr4C9Byb0hyShbnXFoK2EbkuknpEjzmRdccH58yfxITlO6YaVVfNWQvuCHArWaAFtc0T8ufVhdj09s5iXaNM7ug7zFiNmd2vpvlpO0Q_0xGdXshg6hxO9WlJvt9l1bnL5jl5izjb6RMNITyf3Ezubr787v3FIu7gs3qHHl-RgxCnZ4_2-It_OTr-uP1UXX84_r08uqr4GyJXqFHDZKM11j4haiZrXAhlIADtIplQ_MNlBMwJvxrFmMPRCSymbkikYxYp83Olul262Q299jjiZbXQzxjsT0Jm_K95dm024NUpoAJBF4O1eIIYfi03ZzK6MO03obViS4aBl6UZxVtA3_6A3YYm-jHdPCdXWkolC8R1Vvi-laMfHZoCZe0fNzlFTHDUPjpZeVuT10zEer_z2rwBiB6RS8hsb_7z9H9lfLp6tFg</recordid><startdate>20190219</startdate><enddate>20190219</enddate><creator>Lin, Jiun-Nong</creator><creator>Lai, Chung-Hsu</creator><creator>Yang, Chih-Hui</creator><creator>Huang, Yi-Han</creator><creator>Lin, Hsi-Hsun</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20190219</creationdate><title>Genomic Features, Comparative Genomics, and Antimicrobial Susceptibility Patterns of Elizabethkingia bruuniana</title><author>Lin, Jiun-Nong ; Lai, Chung-Hsu ; Yang, Chih-Hui ; Huang, Yi-Han ; Lin, Hsi-Hsun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c511t-6b612476828caaa8635253a01411ed4066cd04b17f127ff501dc3844477ff61f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>45</topic><topic>631/326/1320</topic><topic>631/326/325/1506</topic><topic>Antibiotic resistance</topic><topic>Antibiotics</topic><topic>Antimicrobial agents</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>Gene families</topic><topic>Genes</topic><topic>Genomes</topic><topic>Genomics</topic><topic>Humanities and Social Sciences</topic><topic>Hybridization</topic><topic>Levofloxacin</topic><topic>Minocycline</topic><topic>multidisciplinary</topic><topic>Nucleotide sequence</topic><topic>Phylogeny</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Species</topic><topic>Virulence factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lin, Jiun-Nong</creatorcontrib><creatorcontrib>Lai, Chung-Hsu</creatorcontrib><creatorcontrib>Yang, Chih-Hui</creatorcontrib><creatorcontrib>Huang, Yi-Han</creatorcontrib><creatorcontrib>Lin, Hsi-Hsun</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lin, Jiun-Nong</au><au>Lai, Chung-Hsu</au><au>Yang, Chih-Hui</au><au>Huang, Yi-Han</au><au>Lin, Hsi-Hsun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genomic Features, Comparative Genomics, and Antimicrobial Susceptibility Patterns of Elizabethkingia bruuniana</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2019-02-19</date><risdate>2019</risdate><volume>9</volume><issue>1</issue><spage>2267</spage><epage>2267</epage><pages>2267-2267</pages><artnum>2267</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>Elizabethkingia bruuniana
is a novel species of the
Elizabethkingia
genus. There is scant information on this microorganism. Here, we report the whole-genome features and antimicrobial susceptibility patterns of
E
.
bruuniana
strain EM798-26.
Elizabethkingia
strain EM798-26 was initially identified as
E
.
miricola
. This isolate contained a circular genome of 4,393,011 bp. The whole-genome sequence-based phylogeny revealed that
Elizabethkingia
strain EM798-26 was in the same group of the type strain
E
.
bruuniana
G0146
T
. Both
in silico
DNA-DNA hybridization and average nucleotide identity analysis clearly demonstrated that
Elizabethkingia
strain EM798-26 was a species of
E
.
bruuniana
. The pan-genome analysis identified 2,875 gene families in the core genome and 5,199 gene families in the pan genome of eight publicly available
E
.
bruuniana
genome sequences. The unique genes accounted for 0.2–12.1% of the pan genome in each
E
.
bruuniana
. A total of 59 potential virulence factor homologs were predicted in the whole-genome of
E
.
bruuniana
strain EM798–26. This isolate was nonsusceptible to multiple antibiotics, but susceptible to aminoglycosides, minocycline, and levofloxacin. The whole-genome sequence analysis of
E
.
bruuniana
EM798-26 revealed 29 homologs of antibiotic resistance-related genes. This study presents the genomic features of
E
.
bruuniana
. Knowledge of the genomic characteristics provides valuable insights into a novel species.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>30783197</pmid><doi>10.1038/s41598-019-38998-6</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 2045-2322 |
ispartof | Scientific reports, 2019-02, Vol.9 (1), p.2267-2267, Article 2267 |
issn | 2045-2322 2045-2322 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6381114 |
source | Open Access: PubMed Central; Publicly Available Content (ProQuest); Free Full-Text Journals in Chemistry; Springer Nature - nature.com Journals - Fully Open Access |
subjects | 45 631/326/1320 631/326/325/1506 Antibiotic resistance Antibiotics Antimicrobial agents Deoxyribonucleic acid DNA Gene families Genes Genomes Genomics Humanities and Social Sciences Hybridization Levofloxacin Minocycline multidisciplinary Nucleotide sequence Phylogeny Science Science (multidisciplinary) Species Virulence factors |
title | Genomic Features, Comparative Genomics, and Antimicrobial Susceptibility Patterns of Elizabethkingia bruuniana |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T10%3A16%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Genomic%20Features,%20Comparative%20Genomics,%20and%20Antimicrobial%20Susceptibility%20Patterns%20of%20Elizabethkingia%20bruuniana&rft.jtitle=Scientific%20reports&rft.au=Lin,%20Jiun-Nong&rft.date=2019-02-19&rft.volume=9&rft.issue=1&rft.spage=2267&rft.epage=2267&rft.pages=2267-2267&rft.artnum=2267&rft.issn=2045-2322&rft.eissn=2045-2322&rft_id=info:doi/10.1038/s41598-019-38998-6&rft_dat=%3Cproquest_pubme%3E2183695403%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c511t-6b612476828caaa8635253a01411ed4066cd04b17f127ff501dc3844477ff61f3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2183695403&rft_id=info:pmid/30783197&rfr_iscdi=true |