F64. EXPLORING THE ROLE OF EMOTION DYSREGULATION AND IMPULSIVITY ON SUICIDAL IDEATION AND BEHAVIOR WITHIN AN EARLY PSYCHOSIS POPULATION

• Published in: Schizophrenia bulletin 2019-04, Vol.45 (Supplement_2), p.S279-S279
• Main Authors: Grattan, Rebecca, Tully, Laura, Lesh, Tyler, Carter, Cameron, Niendam, Tara
• Format: Article
• Language: English
• Subjects: Poster Session II
• ISSN: 0586-7614; 1745-1701
• DOI: 10.1093/schbul/sbz018.476

Abstract Background Suicide is a leading cause of death for young people and a challenging clinical issue across diagnostic categories. Historically suicide research has focused on specific diagnostic groups, rather than transdiagnostic risk factors. This has hindered prevention efforts and early identification of those at risk. Emotion dysregulation and impulsivity represent two transdiagnostic risk factors for suicide. While these constructs are often investigated separately, we hypothesized that emotion dysregulation and impulsivity cluster together, and that this combination increases suicidal behavior and ideation. This hypothesis was examined in an early psychosis population, a group at increased risk for suicide, comprised of affective and non-affective diagnoses. Methods Participants were recruited from an Early Psychosis Program (n= 245, ages 12–37, 72% male). Clinician ratings of symptoms (Brief Psychiatric Rating Scale; BPRS) and history of suicidal ideation, behavior and non-suicidal self-injurious behavior (NSSIB; Columbia-Suicide Severity Rating Scale) were obtained at baseline and 12 month follow up. A subset (n= 78, ages 12–32, 62% male) completed self-report measures of emotion dysregulation (subset from Wender Utah Rating Scale) and impulsivity (Barrett Impulsiveness Scale). Regression analyses examined whether emotion dysregulation and impulsivity individually predicted suicidal behavior and ideation at baseline and follow up. Hierarchical cluster analyses of emotion dysregulation and impulsivity detected two distinct groups, and suicide variables were compared across groups. Results In the full sample (N = 245), 52% reported a history of suicidal ideation, 22% reported suicidal behavior and 18% reported NSSIB. In the subset, emotion dysregulation predicted history of suicidal ideation (R2 = .07, F (1,83) = 6.17, p = .02), behavior (R2 = .20, F (1,83) = 21.2, p < .01) and NSSIB (p = .05). When controlling for BPRS score, only the relationship with behavior remained significant. Attention impulsivity scores predicted suicidal ideation (R2 = .55, F (1,127) = 7.34, p = .01) and NSSIB (p = .04) but these were not significant when controlling for BPRS score. Motor and planning impulsivity scores were not related to suicidal ideation, behavior or NSSIB. Cluster analysis identified two groups: an emotionally dysregulated group with high impulsivity and inattention (N = 10), and a more regulated, less impulsive group (N = 68). The dysregulated g