Left atrial size and function in a South Asian population and their potential influence on the risk of atrial fibrillation

Background South Asians have a low prevalence of atrial fibrillation (AF) compared with Caucasians despite having a higher prevalence of conventional risk factors for the arrhythmia. The reason for this disparity is uncertain but may be due to ethnic differences in atrial morphology. This study exam...

Full description

Saved in:
Bibliographic Details
Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2018-10, Vol.41 (10), p.1379-1385
Main Authors: O'Neill, James, Swoboda, Peter P., Plein, Sven, Tayebjee, Muzahir H.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Asian Continental Ancestry Group - ethnology
Asian people
atrial fibrillation
Atrial Fibrillation - diagnosis
Atrial Fibrillation - ethnology
Bangladesh - ethnology
Cardiac arrhythmia
Cardiac Volume - physiology
cardiovascular magnetic resonance imaging
Case-Control Studies
Clinical Investigations
Ethnicity
Female
Follow-Up Studies
Heart Atria - diagnostic imaging
Heart Atria - physiopathology
Humans
Incidence
India - ethnology
left atrial function
left atrial volume
Magnetic Resonance Imaging, Cine
Male
Middle Aged
NMR
Nuclear magnetic resonance
Pakistan - ethnology
Retrospective Studies
Risk Assessment - methods
Risk Factors
United Kingdom - epidemiology
White people
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background South Asians have a low prevalence of atrial fibrillation (AF) compared with Caucasians despite having a higher prevalence of conventional risk factors for the arrhythmia. The reason for this disparity is uncertain but may be due to ethnic differences in atrial morphology. This study examines the association between ethnicity and left atrial (LA) size and function in South Asian and Caucasian subjects using the reference technique of cardiovascular magnetic resonance imaging (MRI). Hypothesis South Asians have smaller LA size and therefore increased LA function. Methods Retrospective case‐control study of 60 South Asian and 60 Caucasian patients who had undergone a clinically indicated MRI between April 2010 and October 2017 and had been found to have a structurally normal heart. LA and left ventricular (LV) volume and function were assessed and compared between the ethnicities. Results In comparison with Caucasians, South Asians had significantly lower minimum (27.7 ± 11.1 mL vs 34.9 ± 12.3 mL, P = 0.002) and maximum LA volumes (64.7 ± 21.1 mL vs 80.9 ± 22.5 mL, P 
ISSN:0160-9289
1932-8737
DOI:10.1002/clc.23064