Influence of age on left atrial appendage function in patients with nonvalvular atrial fibrillation

Background: Age is an independent risk factor for thromboembolism in nonvalvular atrial fibrillation (NVAF). An association between low left atrial appendage (LAA) Doppler velocities and thromboembolic risk in NVAF has been reported. Methods: Forty‐two consecutive patients (age 69 ± 2 years [range 4...

Full description

Saved in:
Bibliographic Details
Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2001-01, Vol.24 (1), p.39-44
Main Authors: Ilercil, Arzu, Kondapaneni, Jyothi, Hla, Aung, Shirani, Jamshid
Format: Article
Language:English
Subjects:
Adult
age
Age Factors
Aged
Atrial Appendage - physiopathology
atrial fibrillation
Atrial Fibrillation - diagnosis
Atrial Fibrillation - diagnostic imaging
Atrial Fibrillation - physiopathology
Atrial Function, Left
Biological and medical sciences
Blood Flow Velocity
Cardiac dysrhythmias
Cardiology. Vascular system
Echocardiography
Echocardiography, Transesophageal
embolism
Female
Heart
Humans
left atrial appendage
Male
Medical sciences
Middle Aged
Risk Factors
Thromboembolism - epidemiology
Thromboembolism - physiopathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: Age is an independent risk factor for thromboembolism in nonvalvular atrial fibrillation (NVAF). An association between low left atrial appendage (LAA) Doppler velocities and thromboembolic risk in NVAF has been reported. Methods: Forty‐two consecutive patients (age 69 ± 2 years [range 42–92], 24 [57%] men) with NVAF underwent transthoracic and transesophageal echocardiography. The following were compared in 22 patients younger and 20 older than 70 years: left ventricular (LV) diameter, mass and ejection fraction, left atrial (LA) diameter and volume, LAA area and volume, LAA peak emptying (PE) and peak filling (PF) velocities, presence and severity of spontaneous echo contrast (SEC) and mitral regurgitation (MR). Results: Left atrial diameter (4.6 ± 0.1 vs. 4.5 ± 0.2 cm), LA volume (105 ± 10 vs. 92 ± 8 ml), LAA area (6.8 ± 0.6 vs. 5.2 ± 0.8 cm), and LAA volume (5.6 ± 0.9 vs. 3.9 ± 1.0 ml) were similar (p>0.05) in both groups. Older patients had lower LAA PE (26 ± 2 vs. 34 ± 3 cm/s, p = 0.02) and PF (32 ± 2 vs. 41 ± 4 cm/s, p = 0.04) velocities, lower LV mass (175 ± 13 vs. 234 ± 21 gm, p = 0.02), higher relative wall thickness (0.52 ± 0.02 vs. 0.43 ± 0.03, p = 0.02), smaller LV diastolic diameter (4.3 ± 0.1 vs. 5.2 ± 0.2 cm, p
ISSN:0160-9289
1932-8737
DOI:10.1002/clc.4960240107