Platelet/Lymphocyte, Lymphocyte/Monocyte, and Neutrophil/Lymphocyte Ratios as Biomarkers in Patients with Rheumatoid Arthritis and Rheumatoid Arthritis-Associated Interstitial Lung Disease

BACKGROUND The objective of this study was to assess the diagnostic value of platelet/lymphocyte ratio (PLR), lymphocyte/monocyte ratio (LMR), and neutrophil/lymphocyte ratio (NLR) as biomarkers in patients with rheumatoid arthritis (RA) and rheumatoid arthritis-associated interstitial lung disease...

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Bibliographic Details
Published in:Medical science monitor 2019-08, Vol.25, p.6474-6481
Main Authors: Chen, Qiang, Chen, Dong-Yu, Xu, Xi-Zhu, Liu, Ying-Ying, Yin, Ting-Ting, Li, Dong
Format: Article
Language:English
Subjects:
Arthritis, Rheumatoid - blood
Arthritis, Rheumatoid - complications
Arthritis, Rheumatoid - pathology
Biomarkers - blood
Blood Platelets - pathology
Clinical Research
Female
Humans
Logistic Models
Lung Diseases, Interstitial - blood
Lung Diseases, Interstitial - complications
Lung Diseases, Interstitial - pathology
Lymphocytes - pathology
Male
Middle Aged
Monocytes - pathology
Neutrophils - pathology
ROC Curve
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Summary:BACKGROUND The objective of this study was to assess the diagnostic value of platelet/lymphocyte ratio (PLR), lymphocyte/monocyte ratio (LMR), and neutrophil/lymphocyte ratio (NLR) as biomarkers in patients with rheumatoid arthritis (RA) and rheumatoid arthritis-associated interstitial lung disease (RA-ILD). MATERIAL AND METHODS Demographic and laboratory data were acquired for 198 RA and 103 RA-ILD patients and 290 healthy controls. The subjects were categorized into female and male groups and further subcategorized based on age into
ISSN:1643-3750
1234-1010
1643-3750
DOI:10.12659/MSM.916583