Glycemic variability is associated with myocardial damage in nondiabetic patients with ST-elevation myocardial infarction

BACKGROUNDGlycemic variability (GV) induces coronary microcirculatory disturbance and myocardial damage in diabetic patients with acute myocardial infarction. However, in nondiabetic acute myocardial infarction patients, the relationship between GV and myocardial damage remains unclear. PATIENTS AND...

Full description

Saved in:
Bibliographic Details
Published in:Cardiovascular endocrinology 2018-06, Vol.7 (2), p.47-53
Main Authors: Oka, Satoshi, Deyama, Juntaro, Umetani, Ken, Harama, Tomoko, Shimizu, Takuya, Makino, Aritaka, Sano, Keita, Nakamura, Masahiko
Format: Article
Language:English
Subjects:
Original
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:BACKGROUNDGlycemic variability (GV) induces coronary microcirculatory disturbance and myocardial damage in diabetic patients with acute myocardial infarction. However, in nondiabetic acute myocardial infarction patients, the relationship between GV and myocardial damage remains unclear. PATIENTS AND METHODSWe investigated GV with a continuous glucose monitoring system in nondiabetic ST-segment elevation myocardial infarction patients treated with emergent percutaneous coronary intervention. GV was expressed as the mean amplitude of glycemic excursions (MAGE). Myocardial damage was estimated by myocardial blush grade and ST-segment resolution (STRes). STRes was defined as complete (>70%), partial (30–70%), or none (
ISSN:2162-688X
2574-0954
2162-688X
2574-0954
DOI:10.1097/XCE.0000000000000145