Metal-enhanced fluorescence using anisotropic silver nanostructures: critical progress to date

In this critical and timely review, the effects of anisotropic silver nanostructures on the emission intensity and photostability of a key fluorophore that is frequently used in many biological assays is examined. The silver nanostructures consist of triangular, rod-like, and fractal-like nanopartic...

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Bibliographic Details
Published in:Analytical and bioanalytical chemistry 2005-06, Vol.382 (4), p.926-933
Main Authors: Aslan, Kadir, Lakowicz, Joseph R, Geddes, Chris D
Format: Article
Language:English
Subjects:
Anisotropy
Biosensing Techniques - methods
Nanostructures - chemistry
Sensitivity and Specificity
Silver - chemistry
Spectrometry, Fluorescence - methods
Surface Properties
Time Factors
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Summary:In this critical and timely review, the effects of anisotropic silver nanostructures on the emission intensity and photostability of a key fluorophore that is frequently used in many biological assays is examined. The silver nanostructures consist of triangular, rod-like, and fractal-like nanoparticles of silver deposited on conventional glass substrates. The close proximity to silver nanostructures results in greater intensity and photostability of the fluorophore than for fluorophores solely deposited on glass substrates. These new anisotropic silver nanostructure-coated surfaces show much more favorable effects than silver island films or silver colloid-coated substrates. Subsequently, the use of metal-enhanced fluorescence (MEF) for biosensing applications is discussed.
ISSN:1618-2642
1618-2650
DOI:10.1007/s00216-005-3195-3