Evaluation of Mucociliary Activity in Maxillary Antra in Patients with Squamous Cell Carcinoma of Buccal Mucosa Undergoing Post Operative Radiotherapy

A prospective longitudinal observational study was conducted on 24 patients of histopathologically confirmed squamous cell carcinoma of buccal mucosa upon whom bilateral ‘middle meatal antrostomy was performed during the same sitting as the tumour resection with the main aim to assess the maxillary...

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Bibliographic Details
Published in:Indian journal of otolaryngology, and head, and neck surgery and head, and neck surgery, 2019-11, Vol.71 (Suppl 3), p.2082-2086
Main Authors: Kadapathri, Abhimanyu, Azeem Mohiyuddin, S. M.
Format: Article
Language:English
Subjects:
Head & neck cancer
Head and Neck Surgery
Histopathology
Maxillofacial surgery
Medicine
Medicine & Public Health
Oral cancer
Original
Original Article
Otorhinolaryngology
Radiation therapy
Squamous cell carcinoma
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Summary:A prospective longitudinal observational study was conducted on 24 patients of histopathologically confirmed squamous cell carcinoma of buccal mucosa upon whom bilateral ‘middle meatal antrostomy was performed during the same sitting as the tumour resection with the main aim to assess the maxillary mucociliary clearance, pre-, during and post-irradiation; and compare the findings with the non-irradiated side in the same patient to avoid any confounding factors. All patients underwent methylene blue dye clearance and saccharine clearance tests before the commencement of radiation therapy, weekly during irradiation and again at first and sixth month of completion of irradiation. Pre-radiation there was statistically no difference ( P  > 0.05) in clearance times between both sides. But, there was a significant ( P  
ISSN:2231-3796
0973-7707
DOI:10.1007/s12070-018-1477-2