PSIV-B-42 Late-Breaking: Effects of dietary inactivated probiotics on growth performance, nutrient digestibility, and immune responses of weaned pigs

• Published in: Journal of animal science 2019-12, Vol.97 (Supplement_3), p.327-328
• Main Authors: Kang, Joowon, Chae, Jong Pyo, Kim, S-H, Kim, J-W, Park, Sangwoo, Mun, Daye, Kim, Byeonghyeon, Kim, Sheena, Lee, Jeongjae, Kim, Soyun, Kyoung, Hyunjin, Choe, Jeehwan, Song, Minho
• Format: Article
• Language: English
• Subjects: POSTER PRESENTATIONS
• ISSN: 0021-8812; 1525-3163
• DOI: 10.1093/jas/skz258.656

The study was conducted to investigate effects of dietary inactivated probiotics on growth performance, nutrient digestibility, and immune responses of weaned pigs. A total of 96 weaned pigs (initial BW = 6.95 ± 0.25 kg) were randomly assigned to 4 dietary treatments with increasing levels of inactive probiotics (4 pigs/replicate; 6 replicates/treatment; 0, 0.1, 0.2, and 0.4%; CON, T1, T2, and T3) in a randomized complete block design (BW and sex as blocks). The inactivated probiotics used in this experiment was a commercial product (CJ CheilJedang Biotechnology Research Institute, Seoul, Korea) containing 1 x 106 CFU/g on stains of Lactobacillus rhamnosus. Pigs were fed respective dietary treatments for 4 weeks. During the last week of the experimental period, pigs were fed their respective dietary treatments containing 0.2% chromic oxide. Fecal samples were collected by rectal palpation daily for the last 3 days after the 4-day adjustment period during the last week of experiment. Blood was collected from randomly selected one pig each pen on d 1, 3, 7, and 14 after weaning. Measurements were growth performance, apparent total tract digestibility (ATTD), TNF-α, TGF-β, CRP, and cortisol by ELISA. Data were analyzed using the MIXED procedure of SAS. The inactivated probiotics increased ADG (471, 501, and 513 vs. 428 g/d; P < 0.05) and G:F (0.65, 0.69, and 0.71 vs. 0.58 g/g; P < 0.05) during overall experimental period compared with CON. The inactivated probiotics increased ATTD of GE (86.87, 87.29, and 88.53 vs. 85.25%; P < 0.05) compared with CON. The inactivated probiotics decreased TNF-α (600, 542, and 523 vs. 849 pg/ml; P < 0.05) and cortisol (5.58, 5.56, and 5.44 vs. 7.25 ng/ml; P < 0.05) on d 7 compared with CON. In conclusion, addition of inactivated probiotics improved growth performance, and nutrient digestibility, and modified immune responses.