Comparison of intervertebral fusion rates of different bone graft materials in extreme lateral interbody fusion

To compare imaging indicators and clinical effects of extreme lateral interbody fusion (XLIF) using allogenic bone, autologous bone marrow + allogenic bone, and rhBMP-2 + allogenic bone as bone graft materials in the treatment of degenerative lumbar diseases.This was a retrospective study of 93 pati...

Full description

Saved in:
Bibliographic Details
Published in:Medicine (Baltimore) 2019-11, Vol.98 (44), p.e17685-e17685
Main Authors: Gao, Yuan, Li, Jiaqi, Cui, Hao, Zhang, Fei, Sun, Yapeng, Li, Zeyang, Ding, Wenyuan, Shen, Yong, Zhang, Wei
Format: Article
Language:English
Subjects:
Adult
Bone Marrow Transplantation - methods
Bone Morphogenetic Protein 2 - administration & dosage
Bone Transplantation - methods
Female
Humans
Intervertebral Disc Degeneration - surgery
Lumbar Vertebrae - surgery
Male
Middle Aged
Observational Study
Pain Measurement
Physical Functional Performance
Recombinant Proteins - administration & dosage
Retrospective Studies
Spinal Fusion - methods
Transforming Growth Factor beta - administration & dosage
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To compare imaging indicators and clinical effects of extreme lateral interbody fusion (XLIF) using allogenic bone, autologous bone marrow + allogenic bone, and rhBMP-2 + allogenic bone as bone graft materials in the treatment of degenerative lumbar diseases.This was a retrospective study of 93 patients with lumbar interbody fusion who underwent the extreme lateral approach from May 2016 to December 2017. According to the different bone graft materials, patients were divided into allogenic bone groups (group A, 31 cases), rhBMP-2 + allogenic bone (group B, 32 cases), and autologous bone marrow + allogenic bone (group C, 30 cases). There were no significant differences in gender, age, lesion segment, preoperative intervertebral space height, and preoperative Oswestry Dysfunction Index (ODI) and visual analogue scale (VAS) scores among the 3 groups (P > .05). Intervertebral space height, bone graft fusion rate, and ODI and VAS scores were compared immediately after surgery, and at 3, 6, and 12 months after surgery.All groups were followed up for 12 months. The intervertebral space height was significantly higher in the 3 groups immediately after surgery and at 3, 6, and 12 months after surgery, in comparison to before surgery (P  .05). The fusion rate of group B and C was higher than that of groups A at 3, 6, and 12 months after surgery (P 
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000017685