Pre-exposure prophylaxis for HIV prevention in East and Southern Africa

Pre-exposure prophylaxis (PrEP) has proven to be highly effective in preventing HIV in uninfected persons when properly adhered to. East and Southern African countries that suffer from high HIV prevalence and incidence are increasingly adopting PrEP as an HIV prevention strategy for their high-risk...

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Bibliographic Details
Published in:Canadian journal of public health 2017-05, Vol.108 (5-6), p.e643-e645
Main Authors: van der Wal, Ran, Loutfi, David
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Adolescent
Africa
Africa, Eastern - epidemiology
Africa, Southern - epidemiology
Aggression
AIDS
Choice Behavior
COMMENTARY
Disease prevention
Drug therapy
Economic factors
Education
Epidemics
Epidemics - prevention & control
Exposure
Female
Gender
Health aspects
Health risks
HIV
HIV (Viruses)
HIV Infections - epidemiology
HIV Infections - prevention & control
Human immunodeficiency virus
Humans
Incidence
Infections
Medicine & Public Health
Populations
Poverty
Power, Psychological
Pre-Exposure Prophylaxis - statistics & numerical data
Prevention
Prophylaxis
Public Health
Risk Assessment
Risk factors
Sexual abuse
Sexual behavior
Sexually abused teenagers
Sexually transmitted diseases
Socioeconomic Factors
STD
Stigma
Systematic review
Treatment Adherence and Compliance - statistics & numerical data
Violence
Women
Young Adult
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Summary:Pre-exposure prophylaxis (PrEP) has proven to be highly effective in preventing HIV in uninfected persons when properly adhered to. East and Southern African countries that suffer from high HIV prevalence and incidence are increasingly adopting PrEP as an HIV prevention strategy for their high-risk populations, including for young women. Structural factors such as poverty, lack of education, and gender-based violence may compromise their PrEP uptake and adherence, however. Choice-disabled young women are most at risk of HIV infection and least able to apply HIV prevention choices. For successful rollout of this biomedical solution, we need structural interventions that address these underlying drivers of the HIV epidemic. Lorsqu’elle est bien suivie, la prophylaxie pré-exposition (PPrE) s’avère hautement efficace pour prévenir le VIH chez les personnes non infectées. Les pays d’Afrique de l’Est et d’Afrique australe aux prises avec des taux élevés de prévalence et d’incidence du VIH adoptent de plus en plus la PPrE comme stratégie de prévention du VIH dans leurs populations à risque élevé, en particulier les jeunes femmes. Les facteurs comme la pauvreté, le manque d’instruction et la violence sexiste peuvent toutefois compromettre l’utilisation et l’observance de la PPrE dans ces populations. Les jeunes femmes défavorisées sur le plan des choix sont les plus vulnérables aux infections à VIH et les moins capables de mettre en pratique les choix de prévention du VIH. Pour un déploiement réussi de cette solution biomédicale, nous avons besoin d’interventions structurelles qui tiennent compte des vecteurs sous-jacents de l’épidémie de VIH.
ISSN:0008-4263
1920-7476
DOI:10.17269/CJPH.108.6254