Effect of Moderate-Intensity Aerobic Exercise on Hepatic Fat Content and Visceral Lipids in Hepatic Patients with Diabesity: A Single-Blinded Randomised Controlled Trial

• Published in: Evidence-based complementary and alternative medicine 2020, Vol.2020 (2020), p.1-7
• Main Authors: Kamel, Dalia M., Ibrahim, Ahmed A., Tantawy, Sayed A., Khalil, Mona A., Elnegamy, Tamer E., Alrawaili, Saud M., Nambi, Gopal, Elsayed, Shereen H., Abdelbasset, Walid Kamal, Soliman, Gaber S.
• Format: Article
• Language: English
• Subjects: Aerobics; Alanine; Blood lipids; Body mass index; Cholesterol; Data analysis; Diabetes; Diabetes mellitus; Exercise; Fatty liver; Fitness training programs; Glycosylated hemoglobin; Hemoglobin; High density lipoprotein; Insulin resistance; Lipids; Lipoproteins; Liver; Liver diseases; Magnetic resonance imaging; Medical research; Medical treatment; Medicine, Experimental; Metabolism; Obesity; Oils & fats; Patients; Physical fitness; Physical therapy; Physical training; Triglycerides; Type 2 diabetes; Womens health
• ISSN: 1741-427X; 1741-4288
• DOI: 10.1155/2020/1923575

Objective. Limited studies have assessed the effect of moderate-intensity continuous aerobic exercise on hepatic fat content and visceral lipids in hepatic patients with diabesity. This study was designed to evaluate hepatic fat content and visceral lipids following moderate-intensity continuous aerobic exercise in hepatic patients with diabesity. Design. A single-blinded randomised controlled trial. Methods. Thirty-one diabetic obese patients with nonalcoholic fatty liver disease were recruited into this study. The patients were randomly classified into exercise and control groups, fifteen patients in the exercise group and sixteen patients in the control group. The exercise group received an 8-week moderate-intensity continuous aerobic exercise program with standard medical treatment, while the control group received standard medical treatment without any exercise program. Hepatic fat content and visceral lipids were assessed before and after intervention at the end of the study. Results. Baseline and clinical characteristics showed a nonsignificant difference between the two groups (p>0.05). At the end of the intervention, the aerobic exercise showed significant improvements (serum triglycerides and low-density lipoproteins (LDLs), p≤0.002, total cholesterol, p=0.004, visceral fats, p=0.016, glycated hemoglobin (HbA1C), p=0.022, high-density lipoproteins (HDLs), p=0.038, alanine transaminases (AL), p=0.044, intrahepatic triglyceride and HOMA-IR, p=0.046, and body mass index (BMI), p=0.047), while the control group showed a nonsignificant difference (p>0.05). The postintervention analysis showed significant differences in favor of the aerobic exercise group (p