Extrapulmonary manifestations of COVID-19: Radiologic and clinical overview

COVID-19 is principally a respiratory illness and pulmonary manifestations constitute main presentations of the disease. According to the reported studies, SARS-CoV-2 infection is not limited to the respiratory system and other organs can be also affected. Renal dysfunction, gastrointestinal complic...

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Bibliographic Details
Published in:Clinical imaging 2020-10, Vol.66, p.35-41
Main Authors: Behzad, Shima, Aghaghazvini, Leila, Radmard, Amir Reza, Gholamrezanezhad, Ali
Format: Article
Language:English
Subjects:
Abnormalities
Betacoronavirus
Cardiovascular disease
Complications
Coronavirus Infections - diagnostic imaging
Coronaviruses
COVID-19
Diagnostic systems
Extrapulmonary manifestation
Gastrointestinal complications
Heart
Hematology
Humans
Liver diseases
Liver dysfunction
Lung - diagnostic imaging
Lymphadenopathy
Mortality
Neurological manifestations
Neurophysiology
Organs
Pandemics
Pericardial effusion
Pneumonia, Viral - diagnostic imaging
Renal dysfunction
Renal function
Respiratory system
SARS-CoV-2
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Tomography, X-Ray Computed
Viral diseases
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Summary:COVID-19 is principally a respiratory illness and pulmonary manifestations constitute main presentations of the disease. According to the reported studies, SARS-CoV-2 infection is not limited to the respiratory system and other organs can be also affected. Renal dysfunction, gastrointestinal complications, liver dysfunction, cardiac manifestations, mediastinal findings, neurological abnormalities, and hematological manifestations are among the reported extrapulmonary features. Considering the broad spectrum of clinical manifestations and the increasing worldwide burden of the disease, there is an urgent need to rapidly scale up the diagnostic capacity to detect COVID-19 and its complications. This paper focuses on the most common extrapulmonary manifestations in patients with COVID-19 pneumonia. Further studies are needed to elaborate and confirm the causative relationship between SARS-CoV-2 and the reported extrapulmonary manifestations of COVID-19. •SARS-CoV-2 infection is not limited to the respiratory system and other organs can be affected.•Renal, gastrointestinal, liver, cardiac, neurological, and hematological complications are among the reported extrapulmonary features.•Further studies are needed to elaborate the causative relationship between SARS-CoV-2 and the reported extrapulmonary manifestations of COVID-19.
ISSN:0899-7071
1873-4499
DOI:10.1016/j.clinimag.2020.05.013