Machine Learning Characterization of COPD Subtypes: Insights From the COPDGene Study

COPD is a heterogeneous syndrome. Many COPD subtypes have been proposed, but there is not yet consensus on how many COPD subtypes there are and how they should be defined. The COPD Genetic Epidemiology Study (COPDGene), which has generated 10-year longitudinal chest imaging, spirometry, and molecula...

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Bibliographic Details
Published in:Chest 2020-05, Vol.157 (5), p.1147-1157
Main Authors: Castaldi, Peter J, Boueiz, Adel, Yun, Jeong, Estepar, Raul San Jose, Ross, James C, Washko, George, Cho, Michael H, Hersh, Craig P, Kinney, Gregory L, Young, Kendra A, Regan, Elizabeth A, Lynch, David A, Criner, Gerald J, Dy, Jennifer G, Rennard, Stephen I, Casaburi, Richard, Make, Barry J, Crapo, James, Silverman, Edwin K, Hokanson, John E
Format: Article
Language:English
Subjects:
CHEST Review
Cluster Analysis
Diagnostic Imaging
Disease Progression
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Machine Learning
Molecular Epidemiology
Phenotype
Pulmonary Disease, Chronic Obstructive - classification
Pulmonary Disease, Chronic Obstructive - epidemiology
Pulmonary Disease, Chronic Obstructive - genetics
Respiratory Function Tests
Online Access:Get full text
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