Optimal Initial Blood Pressure in Intensive Care Unit Patients with Non-Traumatic Intracranial Hemorrhage

Blood pressure (BP) control is crucial for minimizing the risk of mortality and hematoma growth in patients with acute intracranial hemorrhage (ICH). We aimed to determine the optimal BP range associated with improved patient outcomes. From the Medical Information Mart for Intensive Care-III databas...

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Bibliographic Details
Published in:International journal of environmental research and public health 2020-05, Vol.17 (10), p.3436
Main Authors: Wei, Ming-Cheng, Kornelius, Edy, Chou, Ying-Hsiang, Yang, Yi-Sun, Huang, Jing-Yang, Huang, Chien-Ning
Format: Article
Language:English
Subjects:
Age
Blood pressure
Codes
Confidence intervals
Demographics
Diabetes
Hematoma
Hemorrhage
Intensive care
Laboratories
Medical prognosis
Medical research
Mortality
Patients
Physicians
Risk
Sepsis
Statistical analysis
Stroke
Surgery
Vital signs
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Summary:Blood pressure (BP) control is crucial for minimizing the risk of mortality and hematoma growth in patients with acute intracranial hemorrhage (ICH). We aimed to determine the optimal BP range associated with improved patient outcomes. From the Medical Information Mart for Intensive Care-III database, we identified 1493 patients (age, 18-99 years) admitted to the intensive care unit (ICU) with non-traumatic ICH. The 3-day and 14-day mortality of ICU admissions were compared at different BP ranges. Generalized additive models were used to assess the optimal range of initial mean arterial pressure, systolic blood pressure (SBP), and diastolic blood pressure, and these were identified to be 70-100, 120-150, and 60-100 mmHg, respectively. The 3-day or 14-day mortality showed U-shaped correlations with BP ranges. Our results show that an initial SBP between 120 and 150 mmHg is associated with minimal risk of mortality risk. This recommendation can assist physicians to achieve better outcomes for patients with ICH.
ISSN:1660-4601
1661-7827
1660-4601
DOI:10.3390/ijerph17103436