The project REBOOT protocol: Evaluating a personalized inhibitory control training as an adjunct to cognitive behavioral therapy for bulimia nervosa and binge‐eating disorder

Outcomes from cognitive behavioral therapy (CBT) for bulimia nervosa (BN) and binge‐eating disorder (BED) are suboptimal. One potential explanation is that CBT fails to adequately target inhibitory control (i.e., the ability to withhold an automatic response), which is a key maintenance factor for b...

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Bibliographic Details
Published in:The International journal of eating disorders 2020-06, Vol.53 (6), p.1007-1013
Main Authors: Manasse, Stephanie M., Lampe, Elizabeth W., Gillikin, Lindsay, Payne‐Reichert, Adam, Zhang, Fengqing, Juarascio, Adrienne S., Forman, Evan M.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Behavior modification
Binge eating
Binge-Eating Disorder - psychology
binge‐eating disorder
Bulimia
bulimia nervosa
Bulimia Nervosa - psychology
Cognitive behavioral therapy
Cognitive Behavioral Therapy - methods
Cognitive therapy
Eating disorders
Female
Humans
inhibitory control training
Male
Middle Aged
Questionnaires
Research Design
Young Adult
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Summary:Outcomes from cognitive behavioral therapy (CBT) for bulimia nervosa (BN) and binge‐eating disorder (BED) are suboptimal. One potential explanation is that CBT fails to adequately target inhibitory control (i.e., the ability to withhold an automatic response), which is a key maintenance factor for binge eating. Computerized inhibitory control training (ICT) is a promising method for improving inhibitory control but is relatively untested in BN/BED. The present study will evaluate a computer‐based ICT as an adjunct to CBT for BN/BED. Participants with BN (n = 30) or BED (n = 30) will be randomized to 12 weeks of either CBT + ICT or CBT + a sham training. Trainings will be completed daily for 4 weeks and weekly for 8 weeks. Primary aims include the following: (a) confirm target engagement (evaluate whether ICT improves inhibitory control), (b) test target validation (evaluate whether improvements in inhibitory control are associated with improvements in binge eating), and (c) evaluate the incremental efficacy of ICT on binge eating. Secondary aims include the following: (a) evaluate ICT feasibility and acceptability and (b) assess the moderating effects of approach tendencies on highly palatable food, dietary restraint, and diagnosis. Data will be used to shape a fully powered clinical trial designed to assess efficacy and dose–response effects of ICT for BN/BED.
ISSN:0276-3478
1098-108X
DOI:10.1002/eat.23225