Gender‐specific association between body mass index and all‐cause mortality in patients with atrial fibrillation

Background Elevated body mass index (BMI) is related with reduced mortality in various cardiovascular diseases. Hypothesis Gender‐specific association between BMI and mortality exists in atrial fibrillation (AF). Methods In this multicenter observational study with a mean follow‐up of 1 year, a tota...

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Bibliographic Details
Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2020-07, Vol.43 (7), p.706-714
Main Authors: Lyu, Si‐qi, Yang, Yan‐min, Zhu, Jun, Wang, Juan, Wu, Shuang, Zhang, Han, Shao, Xing‐hui, Ren, Jia‐meng
Format: Article
Language:English
Subjects:
all‐cause mortality
Anticoagulants
atrial fibrillation
Body mass index
Cardiovascular disease
Clinical Investigations
Congenital diseases
gender
Health risk assessment
Mortality
Obesity
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Summary:Background Elevated body mass index (BMI) is related with reduced mortality in various cardiovascular diseases. Hypothesis Gender‐specific association between BMI and mortality exists in atrial fibrillation (AF). Methods In this multicenter observational study with a mean follow‐up of 1 year, a total of 1991 AF patients were enrolled and divided into two groups based on the gender. The primary endpoint was all‐cause mortality while the secondary endpoints were defined as cardiovascular mortality, stroke, and major adverse events during 1‐year follow‐up. Cox regression was performed to identify the association between BMI and clinical outcomes according to gender. Results Female patients with AF tended to be older (P = .027) and thinner (P
ISSN:0160-9289
1932-8737
DOI:10.1002/clc.23371