Repeatability, reproducibility, and comparison of ocular biometry using a new optical coherence tomography-based system and another device

• Published in: Scientific reports 2020-09, Vol.10 (1), p.14440-14440, Article 14440
• Main Authors: Wylęgała, Adam, Bolek, Bartłomiej, Mazur, Robert, Wylęgała, Edward
• Format: Article
• Language: English
• Subjects: 692/308; 692/308/575; Adolescent; Adult; Aged; Aged, 80 and over; Anterior Chamber - diagnostic imaging; Anterior Chamber - pathology; Anterior Chamber - surgery; Apoptosis; Axial Length, Eye - diagnostic imaging; Axial Length, Eye - pathology; Axial Length, Eye - surgery; Biometry; Cataract - diagnostic imaging; Cataract - pathology; Cataract Extraction; Cataracts; CCR5 protein; CD4 antigen; CD8 antigen; Cell activation; Cornea - diagnostic imaging; Cornea - pathology; Cornea - surgery; Female; Haplotypes; Humanities and Social Sciences; Humans; Interferometry - methods; Lymphocytes; Lymphocytes T; Male; Middle Aged; multidisciplinary; Peripheral blood; Reproducibility; Science; Science (multidisciplinary); Tomography, Optical Coherence; Young Adult
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-020-71192-7

Precise measurement of axial length before cataract surgery is necessary for the proper lens implantation. We included 100 eyes of 56 patients in the study. The mean age was 41 (15–84 years). Measurements of axial length, anterior chamber depth (ACD) carried out with the new Revo NX were compared with those obtained with the IOLMaster 500. Interoperator testing was performed on 56 eyes of 56 participants. To test repeatability, axial length, ACD, central corneal thickness, and lens thickness were used. Inter-operator reproducibility was also assessed. The results were evaluated using Bland–Altman analyses. The mean ACD measured with the IOLMaster and Revo NX was 3.41 and 3.40 mm p  = 0.467, respectively. The interclass correlation was excellent at the level of 0.975. ICC for axial length values was 0.999, and the mean was equal to 23.47 for the new device and 23.48 for IOLMaster. ICC for Inter-operator repeatability was higher than 0.99 in all parameters. Revo NX showed a very high level of repeatability with ICC ranging from 0.9929 for central corneal thickness to 0.9997 for axial length. Both devices showed excellent agreement and differences that are insignificant, which suggests that they can be used interchangeably.