Parasitic Infection Surveillance in Mississippi Delta Children

Some recent studies suggest ongoing transmission of parasitic diseases in the American South; however, surveys in Mississippi children are lacking. We enrolled 166 children (median age 8 years, range 4-13 years) from the Mississippi Delta region and carried out multi-parallel real-time polymerase ch...

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Bibliographic Details
Published in:The American journal of tropical medicine and hygiene 2020-09, Vol.103 (3), p.1150-1153
Main Authors: Bradbury, Richard S, Arguello, Irene, Lane, Meredith, Cooley, Gretchen, Handali, Sukwan, Dimitrova, Silvia D, Nascimento, Fernanda S, Jameson, Sam, Hellmann, Kathryn, Tharp, Michelle, Byers, Paul, Montgomery, Susan P, Haynie, Lisa, Kirmse, Brian, Pilotte, Nils, Williams, Steven A, Hobbs, Charlotte V
Format: Article
Language:English
Subjects:
Adolescent
Animals
Cats
Child
Child, Preschool
Dogs
Epidemiological Monitoring
Female
Humans
Male
Mississippi - epidemiology
Parasites - genetics
Parasites - immunology
Parasites - isolation & purification
Parasitic diseases
Parasitic Diseases - epidemiology
Parasitic Diseases - parasitology
Pilot Projects
Seroepidemiologic Studies
Serology
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Summary:Some recent studies suggest ongoing transmission of parasitic diseases in the American South; however, surveys in Mississippi children are lacking. We enrolled 166 children (median age 8 years, range 4-13 years) from the Mississippi Delta region and carried out multi-parallel real-time polymerase chain reaction (PCR) for , , and on their stool samples. Dried blood spots were obtained for multiplex serology antibody detection. Of 166 children, all reported having flushable toilets, 11% had soil exposure, and 34% had a pet dog or cat. None had prior diagnosis or treatment of parasitic disease. Multi-parallel real-time PCRs were negative on the 89 stool DNA extracts available for testing. Dried blood spot testing of all 166 children determined the seroprevalence of IgG antibodies to spp (3.6%), (2.4%), , , and (all 0%). In conclusion, parasitic infections and exposure were scarce in this population. Larger studies of at-risk populations are needed.
ISSN:0002-9637
1476-1645
DOI:10.4269/ajtmh.20-0026