Dying ‘due to’ or ‘with’ COVID-19: a cause of death analysis in hospitalised patients

The SARS-CoV-2 pandemic is accompanied by an ever-rising death toll attributed to coronavirus disease 2019 (COVID-19), but questions have persisted regarding deaths formally attributed to COVID-19. We aimed to provide an independent review of clinical features of patients who died during hospitalisa...

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Bibliographic Details
Published in:Clinical medicine (London, England) England), 2020-09, Vol.20 (5), p.e189-e190
Main Authors: Slater, Thomas A, Straw, Sam, Drozd, Michael, Kamalathasan, Stephe, Cowley, Alice, Witte, Klaus K
Format: Article
Language:English
Subjects:
coronavirus
Coronaviruses
COVID-19
COVID-19 rapid report
Infections
Mortality
Oxygen therapy
Pandemics
Public health
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
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Summary:The SARS-CoV-2 pandemic is accompanied by an ever-rising death toll attributed to coronavirus disease 2019 (COVID-19), but questions have persisted regarding deaths formally attributed to COVID-19. We aimed to provide an independent review of clinical features of patients who died during hospitalisation with a positive PCR test for SARS-CoV-2 and relate these to the reported cause of death. Between 23 March and 28 April 2020, a total of 162 patients with a positive SARS-CoV-2 PCR died in our NHS trust. COVID-19 infection was documented as the direct cause of death in 150 (93%). Review of the records revealed 138 (92%) patients had pulmonary infiltrates on chest radiography, and 146 (97%) required oxygen therapy. This retrospective review of cause of death has demonstrated that the overwhelming majority of hospitalised patients with positive SARS-CoV-2 PCR died as a direct consequence of COVID-19 infection.
ISSN:1470-2118
1473-4893
DOI:10.7861/clinmed.2020-0440