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Association between biphasic reactions and the systems of symptoms and treatment in patients with anaphylaxis hospitalized from the emergency department
We found no association between the number of systems of symptoms and the incidence of biphasic reactions. Currently, predicting the onset of biphasic reactions is difficult. Further prospective and nationwide studies are required to research biphasic reactions. Aim Anaphylaxis is a severe, life‐thr...
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Published in: | Acute medicine & surgery 2020-01, Vol.7 (1), p.e599-n/a |
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Main Authors: | , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | We found no association between the number of systems of symptoms and the incidence of biphasic reactions. Currently, predicting the onset of biphasic reactions is difficult. Further prospective and nationwide studies are required to research biphasic reactions.
Aim
Anaphylaxis is a severe, life‐threatening, generated or systemic reaction, and biphasic reaction could occur in some cases. We investigated the clinical course of anaphylaxis in our hospital and studied the relationship between biphasic reactions and the symptoms and treatments for predicting the onset of biphasic reactions.
Methods
We retrospectively reviewed the medical records of 120 patients with anaphylaxis who were admitted to our hospital from the emergency department during April 2008–October 2015.
Results
The incidence of biphasic reactions of anaphylaxis in our hospital was 10.8% (13 patients) without significant difference when compared with that in previous reports. Regarding the development of biphasic reactions, symptoms, the number of systems of symptoms and severity of the initial reaction, and treatment with adrenaline and corticosteroid were not clearly related with biphasic reaction. Use of adrenaline in the initial treatment was approximately 60%. Of the 13 biphasic reactions, 11 (84.5%) were as equal/mild as the original symptoms.
Conclusion
This study could not show the factors predicting the onset of biphasic reactions. Further prospective and nationwide studies are required to research biphasic reactions. |
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ISSN: | 2052-8817 2052-8817 |
DOI: | 10.1002/ams2.599 |