The COVID-19 Trial Finder

Abstract Clinical trials are the gold standard for generating reliable medical evidence. The biggest bottleneck in clinical trials is recruitment. To facilitate recruitment, tools for patient search of relevant clinical trials have been developed, but users often suffer from information overload. Wi...

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Bibliographic Details
Published in:Journal of the American Medical Informatics Association 2021-03, Vol.28 (3), p.616-621
Main Authors: Sun, Yingcheng, Butler, Alex, Lin, Fengyang, Liu, Hao, Stewart, Latoya A, Kim, Jae Hyun, Idnay, Betina Ross S, Ge, Qingyin, Wei, Xinyi, Liu, Cong, Yuan, Chi, Weng, Chunhua
Format: Article
Language:English
Subjects:
Abstracting and Indexing
Adult
Aged
Aged, 80 and over
Brief Communication
Child, Preschool
Clinical Trials as Topic
COVID-19
Eligibility Determination
Female
Humans
Information Storage and Retrieval
Male
Middle Aged
Patient Selection
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Summary:Abstract Clinical trials are the gold standard for generating reliable medical evidence. The biggest bottleneck in clinical trials is recruitment. To facilitate recruitment, tools for patient search of relevant clinical trials have been developed, but users often suffer from information overload. With nearly 700 coronavirus disease 2019 (COVID-19) trials conducted in the United States as of August 2020, it is imperative to enable rapid recruitment to these studies. The COVID-19 Trial Finder was designed to facilitate patient-centered search of COVID-19 trials, first by location and radius distance from trial sites, and then by brief, dynamically generated medical questions to allow users to prescreen their eligibility for nearby COVID-19 trials with minimum human computer interaction. A simulation study using 20 publicly available patient case reports demonstrates its precision and effectiveness.
ISSN:1527-974X
1067-5027
1527-974X
DOI:10.1093/jamia/ocaa304