Clinical management of the most common extra-intestinal manifestations in patients with inflammatory bowel disease focused on the joints, skin and eyes

Extra-intestinal manifestations (EIMs) of inflammatory bowel disease (IBD) occur frequently and contribute to morbidity and reduced quality of life. The musculoskeletal, ocular and cutaneous organ systems are frequently involved in IBD-related EIMs. By focusing on manifestations involving the joints...

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Bibliographic Details
Published in:United European Gastroenterology Journal 2020-11, Vol.8 (9), p.1031-1044
Main Authors: Jansen, Fenna M, Vavricka, Stephan R, den Broeder, Alfons A, de Jong, Elke MGJ, Hoentjen, Frank, van Dop, Willemijn A
Format: Article
Language:English
Subjects:
Crohn’s disease
cutaneous manifestation
extra‐intestinal manifestation
Inflammatory Bowel Disease
musculoskeletal manifestation
ocular manifestation
therapy
treatment
ulcerative colitis
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Summary:Extra-intestinal manifestations (EIMs) of inflammatory bowel disease (IBD) occur frequently and contribute to morbidity and reduced quality of life. The musculoskeletal, ocular and cutaneous organ systems are frequently involved in IBD-related EIMs. By focusing on manifestations involving the joints, skin and eyes, this review will discuss the most common clinically relevant and burdensome EIMs that affect IBD patients, and strives for early recognition, adequate treatment and timely referral. For this purpose, we aimed to create a comprehensive overview on this topic, with the main focus on the treatment of reactive and associated EIMs, including spondyloarthropathies, pyoderma gangrenosum, erythema nodosum, psoriasis and anterior uveitis. The recently developed biologicals enable simultaneous treatment of inflammatory disorders. This review can be used as a helpful guide in daily clinical practice for physicians who are involved in the treatment of IBD patients.
ISSN:2050-6406
2050-6414
DOI:10.1177/2050640620958902