The Genomic Impact of Selection for Virulence against Resistance in the Potato Cyst Nematode, Globodera pallida

Although the use of natural resistance is the most effective management approach against the potato cyst nematode (PCN) , the existence of pathotypes with different virulence characteristics constitutes a constraint towards this goal. Two resistance sources, (from ) and from ssp. CPC2802 (from the C...

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Bibliographic Details
Published in:Genes 2020-11, Vol.11 (12), p.1429
Main Authors: Varypatakis, Kyriakos, Véronneau, Pierre-Yves, Thorpe, Peter, Cock, Peter J A, Lim, Joanne Tze-Yin, Armstrong, Miles R, Janakowski, Sławomir, Sobczak, Mirosław, Hein, Ingo, Mimee, Benjamin, Jones, John T, Blok, Vivian C
Format: Article
Language:English
Subjects:
Animals
Aqueous solutions
Cultivars
Deoxyribonucleic acid
Digital cameras
Disease Resistance
DNA
Gene frequency
Genes
Genomes
Genomic islands
Genotype & phenotype
Globodera pallida
Nematoda - genetics
Nematoda - pathogenicity
Nematodes
Pathogens
Pest resistance
Plant breeding
Plant Diseases - genetics
Plant Diseases - parasitology
Plant resistance
Population
Population genetics
Potatoes
Solanum tuberosum
Solanum tuberosum - parasitology
Solanum vernei
Virulence
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Summary:Although the use of natural resistance is the most effective management approach against the potato cyst nematode (PCN) , the existence of pathotypes with different virulence characteristics constitutes a constraint towards this goal. Two resistance sources, (from ) and from ssp. CPC2802 (from the Commonwealth Potato Collection) are widely used in potato breeding programmes in European potato industry. However, the use of resistant cultivars may drive strong selection towards virulence, which allows the increase in frequency of virulent alleles in the population and therefore, the emergence of highly virulent nematode lineages. This study aimed to identify ( ) genes in populations selected for virulence on the above resistance sources, and the genomic impact of selection processes on the nematode. The selection drive in the populations was found to be specific to their genetic background. At the genomic level, 11 genes were found that represent candidate genes. Most of the variant calls determining selection were associated with -selected populations, while many of them seem to be organised in genomic islands facilitating selection evolution. These phenotypic and genomic findings combined with histological studies performed revealed potential mechanisms underlying selection in .
ISSN:2073-4425
2073-4425
DOI:10.3390/genes11121429