Cohort profile: the Diet and Healthy Aging (DaHA) study in Singapore

How diet is related with cognition and health has not been systematically examined in Asians whose eating habits are very different from their counterparts in the West and the biological mechanisms underlying such links are not well known yet. The diet and healthy aging (DaHA) study is a community-b...

Full description

Saved in:
Bibliographic Details
Published in:Aging (Albany, NY.) NY.), 2020-11, Vol.12 (23), p.23889-23899
Main Authors: Yu, Rongjun, Sun, Ye, Ye, Kaisy Xinhong, Feng, Qiushi, Lim, Su Lin, Mahendran, Rathi, Cheah, Irwin Kee-Mun, Foo, Roger Sik Yin, Chua, Ru Yuan, Gwee, Xinyi, Loh, Marie, Sarmugam, Rani, Khine, Wei Wei Thwe, Chao, Yin Xia, Larbi, Anis, Lee, Yuan Kun, Kumar, Alan Prem, Kennedy, Brian K, Kua, Ee Heok, Feng, Lei
Format: Article
Language:English
Subjects:
Age Factors
Aged
Aged, 80 and over
Apolipoproteins E - genetics
Cognition
Diet, Healthy
DNA Methylation
Emotions
Feeding Behavior
Female
Healthy Aging - genetics
Healthy Aging - psychology
Humans
Longitudinal Studies
Male
Mental Health
Middle Aged
Nutrition Surveys
Nutritional Status
Nutritive Value
Polymorphism, Genetic
Research Paper
Risk Reduction Behavior
Singapore
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:How diet is related with cognition and health has not been systematically examined in Asians whose eating habits are very different from their counterparts in the West and the biological mechanisms underlying such links are not well known yet. The diet and healthy aging (DaHA) study is a community-based longitudinal study conducted to examine the role of diet and nutrition in promoting cognitive, emotional, and physical health among community-living elderly Singaporeans. The first wave of DaHA, conducted from 2011 to 2017, provided detailed information on diet and baseline cognitive function and health from 1010 community-living elderly in Singapore. Biomarkers of oxidative stress, systemic inflammation, and genetic information were collected. The ongoing second wave of DaHA is conducted from 2017 to 2020, which provides follow- up assessments using established cognitive tests and clinical tools. This well-characterized cohort, with its archived biological samples and high-quality data on diet and lifestyle factors will allow researchers to explore the relationships among diet, nutrition, genes, cognition, mental and physical health in an extremely cost-effective manner. Translations of the research findings into clinical and public health practices will potentially help to promote cognitive health at the population level and reduce healthcare costs related to cognitive impairment.
ISSN:1945-4589
1945-4589
DOI:10.18632/aging.104051