Risk Factors of Clonorchis sinensis Human Infections in Endemic Areas, Haman-Gun, Republic of Korea: A Case-Control Study

Clonorchis sinensis is the most common fish-borne intestinal parasite in Korea. The aim of the present investigation was to survey the status of C. sinensis infection and analyze associated risk factors in residents of Haman-gun, Gyeongsangnam-do. A total of 5,114 residents from 10 administrative to...

Full description

Saved in:
Bibliographic Details
Published in:Korean journal of parasitology 2020, Hosts and Diseases, 58(6), , pp.647-652
Main Authors: Lee, Sang-Eun, Shin, Hee-Eun, Lee, Myoung-Ro, Kim, Yang-Hee, Cho, Shin-Hyeong, Ju, Jung-Won
Format: Article
Language:English
Subjects:
Adult
Aged
Animals
Case-Control Studies
Clonorchiasis - epidemiology
Clonorchiasis - parasitology
Clonorchiasis - prevention & control
Clonorchis sinensis
Feces - parasitology
Feeding Behavior - physiology
Female
Fishes - parasitology
Humans
Male
Middle Aged
Original
Parasite Egg Count
Republic of Korea - epidemiology
Risk Factors
Sex Factors
Surveys and Questionnaires
예방의학
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Clonorchis sinensis is the most common fish-borne intestinal parasite in Korea. The aim of the present investigation was to survey the status of C. sinensis infection and analyze associated risk factors in residents of Haman-gun, Gyeongsangnam-do. A total of 5,114 residents from 10 administrative towns/villages voluntarily agreed to participate in the study, which comprised fecal examination, a questionnaire survey for risk factors, ultrasonography, and enzymelinked immunosorbent assay for cancer biomarker detection in the blood. We detected C. sinensis eggs in 5.3% of the subjects. By region, Gunbuk-myeon had the highest number of residents with C. sinensis eggs. The infection rate and intensity were higher in male than in female residents. Based on the risk factor questionnaire, infection was highly associated with drinking, a history of C. sinensis infection, and the practice of eating of raw freshwater fish. Extension of the bile duct, infection intensity, and cancer biomarker detection significantly correlated with the presence of eggs in the study population. In conclusion, the development of feasible, long-term control policies and strategies for the elimination of C. sinensis in Korea is still required.
ISSN:0023-4001
2982-5164
1738-0006
2982-6799
DOI:10.3347/kjp.2020.58.6.647