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Minimum Effective Analgesic Concentration of Ropivacaine in Saphenous Block Guided by Ultrasound for Knee Arthroscopic Meniscectomy: Randomized, Double-Blind Study

After knee surgery, analgesia should be effective for mobilization and discharge. The primary objective of this study was to achieve the lowest effective analgesic concentration (MEC50 and MEC90) of ropivacaine for saphenous nerve block in arthroscopic meniscectomy. The secondary objective was to de...

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Bibliographic Details
Published in:Journal of pain research 2021-01, Vol.14, p.53-59
Main Authors: Rey Moura, Ed Carlos, de Oliveira, Caio Marcio Barros, da Cunha Leal, Plinio, Kimiko Sakata, Rioko
Format: Article
Language:English
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Summary:After knee surgery, analgesia should be effective for mobilization and discharge. The primary objective of this study was to achieve the lowest effective analgesic concentration (MEC50 and MEC90) of ropivacaine for saphenous nerve block in arthroscopic meniscectomy. The secondary objective was to determine whether the block causes muscle weakness in the postoperative period. The study was randomized, comparative, and double-blind. Fifty-one patients between 18 and 65 years old of both sexes, ASA I or II, who underwent knee arthroscopic meniscectomy at São Domingos Hospital were included. Patients underwent saphenous nerve block with 10 mL of ropivacaine administered by using the up-and-down method. The ropivacaine concentration was determined based on the previous patient's response (a biased-coin up-down design sequential method). If a patient had a negative response, the concentration of ropivacaine was increased by 0.05% in the next patient; if the response was positive, the next patient was randomized to be administered the same concentration of ropivacaine or a 0.05% lower concentration. Successful block was defined as pain
ISSN:1178-7090
1178-7090
DOI:10.2147/JPR.S282286