A Novel MRI Biomarker of Spinal Cord White Matter Injury: T2-Weighted White Matter to Gray Matter Signal Intensity Ratio

T2*-weighted imaging provides sharp contrast between spinal cord GM and WM, allowing their segmentation and cross-sectional area measurement. Injured WM demonstrates T2*WI hyperintensity but requires normalization for quantitative use. We introduce T2*WI WM/GM signal-intensity ratio and compare it a...

Full description

Saved in:
Bibliographic Details
Published in:American journal of neuroradiology : AJNR 2017-06, Vol.38 (6), p.1266-1273
Main Authors: Martin, A.R., De Leener, B., Cohen-Adad, J., Cadotte, D.W., Kalsi-Ryan, S., Lange, S.F., Tetreault, L., Nouri, A., Crawley, A., Mikulis, D.J., Ginsberg, H., Fehlings, M.G.
Format: Article
Language:English
Subjects:
Adult
Aged
Anatomy, Cross-Sectional
Anisotropy
Biomarkers
Central nervous system diseases
Correlation analysis
Damage detection
Diagnosis
Diagnostic systems
Diffusion Tensor Imaging
Disability Evaluation
Female
Gray Matter - diagnostic imaging
Humans
Image processing
Image Processing, Computer-Assisted
Image segmentation
Injuries
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Magnetization
Male
Mathematical models
Middle Aged
Regression analysis
Reproducibility of Results
Spinal cord
Spinal Cord - diagnostic imaging
Spinal Cord Compression - diagnostic imaging
Spinal cord injuries
Spinal Cord Injuries - diagnostic imaging
Spine
Substantia alba
Substantia grisea
White Matter - diagnostic imaging
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!