Gluten intake and metabolic health: conflicting findings from the UK Biobank

Purpose The impact of gluten intake on metabolic health in subjects without celiac disease is unclear. The present study aimed to assess the association between gluten intake and body fat percentage (primary objective), as well as a broad set of metabolic health markers. Methods Gluten intake was es...

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Bibliographic Details
Published in:European journal of nutrition 2021-04, Vol.60 (3), p.1547-1559
Main Authors: Behrendt, Inken, Fasshauer, Mathias, Eichner, Gerrit
Format: Article
Language:English
Subjects:
Biobanks
Biological Specimen Banks
Body fat
Body Mass Index
Celiac disease
Chemistry
Chemistry and Materials Science
Cholesterol
Cross-Sectional Studies
Female
Females
Glomerular filtration rate
Gluten
Glutens
Humans
Hypertension
Male
Males
Metabolic disorders
Metabolism
Nutrition
Obesity
Original Contribution
Regression analysis
Triglycerides
United Kingdom - epidemiology
Waist Circumference
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Summary:Purpose The impact of gluten intake on metabolic health in subjects without celiac disease is unclear. The present study aimed to assess the association between gluten intake and body fat percentage (primary objective), as well as a broad set of metabolic health markers. Methods Gluten intake was estimated in 39,927 participants of the UK Biobank who completed a dietary questionnaire for assessment of previous 24-h dietary intakes. Multiple linear regression analyses were performed between gluten intake and markers of metabolic health with Holm adjustment for multiple comparisons. Results Median gluten intake was 9.7 g/day (male: 11.7 g/day; female: 8.2 g/day; p  
ISSN:1436-6207
1436-6215
DOI:10.1007/s00394-020-02351-9