Prospectively ascertained mania and hypomania among young adults with child‐ and adolescent‐onset bipolar disorder

Objectives While adults with bipolar disorder (BD) often report symptoms starting in childhood, continuity of mania and/or hypomania (mania/hypomania) from childhood to adulthood has been questioned. Using longitudinal data from the Course and Outcome of Bipolar Youth (COBY) study, we assessed thres...

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Bibliographic Details
Published in:Bipolar disorders 2021-08, Vol.23 (5), p.463-473
Main Authors: Hafeman, Danella M., Goldstein, Tina R., Strober, Michael, Merranko, John, Gill, Mary Kay, Liao, Fangzi, Diler, Rasim S., Ryan, Neal D., Goldstein, Benjamin I., Axelson, David A., Keller, Martin B., Hunt, Jeffrey I., Hower, Heather, Weinstock, Lauren M., Yen, Shirley, Birmaher, Boris
Format: Article
Language:English
Subjects:
Adolescents
Affective disorders
Bipolar disorder
child and adolescent
Child development
Children
Children & youth
hypomania
Longitudinal studies
longitudinal study
mania
predictors
Suicide
young adulthood
Young adults
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Summary:Objectives While adults with bipolar disorder (BD) often report symptoms starting in childhood, continuity of mania and/or hypomania (mania/hypomania) from childhood to adulthood has been questioned. Using longitudinal data from the Course and Outcome of Bipolar Youth (COBY) study, we assessed threshold mania/hypomania in young adults who manifested BD as youth. Methods: COBY is a naturalistic, longitudinal study of 446 youth with BD (84% recruited from outpatient clinics), 7–17 years old at intake, and over 11 years of follow‐up. Focusing on youth with BD‐I/II (n = 297), we examined adult mania/hypomania risk (>18 years old; mean 7.9 years of follow‐up) according to child (
ISSN:1398-5647
1399-5618
DOI:10.1111/bdi.13034