Host population dynamics in the face of an evolving pathogen

• Published in: The Journal of animal ecology 2021-06, Vol.90 (6), p.1480-1491
• Main Authors: Hochachka, Wesley M., Dobson, Andrew P., Hawley, Dana M., Dhondt, André A.
• Format: Article
• Language: English
• Subjects: arms race; Bacteria; Birds; Ecological effects; emerging disease; Evolution; Feeders; house finch Haemorhous mexicanus; Immunity; Mycoplasma gallisepticum; Pathogens; Population; Population density; Population dynamics; population limitation; Vertebrates; Virulence
• ISSN: 0021-8790; 1365-2656
• DOI: 10.1111/1365-2656.13469

Interactions between hosts and pathogens are dynamic at both ecological and evolutionary levels. In the resultant ‘eco‐evolutionary dynamics’ ecological and evolutionary processes affect each other. For example, the house finch Haemorhous mexicanus and its recently emerged pathogen, the bacterium Mycoplasma gallisepticum, form a system in which evidence suggests that changes in bacterial virulence through time enhance levels of host immunity in ways that drive the evolution of virulence in an arms race. We use data from two associated citizen science projects in order to determine whether this arms race has had any detectable effect at the population level in the north‐eastern United States. We used data from two citizen science projects, based on observations of birds at bird feeders, which provide information on the long‐term changes in sizes of aggregations of house finches (host population density), and the probabilities that these house finches have observable disease (disease prevalence). The initial emergence of M. gallisepticum caused a rapid halving of house finch densities; this was then followed by house finch populations remaining stable or slowly declining. Disease prevalence also decreased sharply after the initial emergence and has remained low, although with fluctuations through time. Surprisingly, while initially higher local disease prevalence was found at sites with higher local densities of finches, this relationship has reversed over time. The ability of a vertebrate host species, with a generation time of at least 1 year, to maintain stable populations in the face of evolved higher virulence of a bacterium, with generation times measurable in minutes, suggests that genetic changes in the host are insufficient to explain the observed population‐level patterns. We suggest that acquired immunity plays an important role in the observed interaction between house finches and M. gallisepticum. The authors examine the long‐term consequences to house finches of the emergence of a new bacterial pathogen that has increased in potential virulence after it initially killed roughly half of eastern North America's house finches. An apparent immunological arms race has enabled the finches to persist at stable, albeit relatively low, abundance.