Adult cerebrovascular disease: role of modified rapid fluid-attenuated inversion-recovery sequences

To compare a rapid fluid-attenuated inversion-recovery (FLAIR) sequence with T1-weighted, fast spin-echo proton density-weighted, and T2-weighted images in the evaluation of cerebrovascular disease. All patients underwent standard T1-, proton density-, and T2-weighted fast spin-echo and fast FLAIR M...

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Bibliographic Details
Published in:American journal of neuroradiology 1996-09, Vol.17 (8), p.1507-1513
Main Authors: Alexander, JA, Sheppard, S, Davis, PC, Salverda, P
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Brain - pathology
Cerebral Infarction - diagnosis
Cerebral Infarction - pathology
Cerebral Ventricles - pathology
Cerebrovascular Disorders - diagnosis
Cerebrovascular Disorders - pathology
Clinical Trial
Comparative Study
Controlled Clinical Trial
Female
Humans
Image Enhancement - methods
Ischemic Attack, Transient - diagnosis
Ischemic Attack, Transient - pathology
Magnetic Resonance Imaging - methods
Male
Medical sciences
Middle Aged
Neurology
Pons - pathology
Prospective Studies
Protons
Single-Blind Method
Time Factors
Vascular diseases and vascular malformations of the nervous system
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Summary:To compare a rapid fluid-attenuated inversion-recovery (FLAIR) sequence with T1-weighted, fast spin-echo proton density-weighted, and T2-weighted images in the evaluation of cerebrovascular disease. All patients underwent standard T1-, proton density-, and T2-weighted fast spin-echo and fast FLAIR MR imaging at 1.5 T. Images were compared for lesion size, location, and conspicuity. Forty-five infarctions were identified on T2-weighted and fast FLAIR sequences. Lesion size was comparable on the proton density-weighted, fast T2-weighted, and fast FLAIR sequences, although lesion conspicuity was superior on the fast FLAIR images in 43 (96%) of the lesions. Associated periventricular and pontine hyperintensities were more extensive on the fast FLAIR images. Our modified fast FLAIR technique provided improved conspicuity of infarctions and white matter disease as compared with T1-, proton density-, and T2-weighted spin-echo images, and a reduced scan time compared with conventional FLAIR sequences in patients with cerebrovascular disease.
ISSN:0195-6108
1936-959X