Impact of regionalizing ST‐elevation myocardial infarction care on sex differences in reperfusion times and clinical outcomes

Background Women with ST‐elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention historically experience worse in‐hospital outcomes compared to men. Hypothesis Implementation of a regional STEMI system will reduce care gaps in reperfusion times and in‐hospital...

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Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2021-08, Vol.44 (8), p.1113-1119
Main Authors: Rayner‐Hartley, Erin, Wong, Graham C., Fayowski, Cassandra, Cairns, John A., Singer, Joel, Lee, Terry, Sedlak, Tara, Humphries, Karin H., Perry‐Arnesen, Michele, Mackay, Martha, Fordyce, Christopher B.
Format: Article
Language:English
Subjects:
Angioplasty
Blood pressure
Clinical Investigations
Comparative analysis
Diabetes
Emergency medical services
Gender differences
Heart attack
Heart attacks
Heart failure
Hemoglobin
Hospitals
Hypertension
Mortality
Patient outcomes
Patients
sex differences
Sexes
ST‐elevation myocardial infarction
systems implementation
Transient ischemic attack
Transluminal angioplasty
Variables
Womens health
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Summary:Background Women with ST‐elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention historically experience worse in‐hospital outcomes compared to men. Hypothesis Implementation of a regional STEMI system will reduce care gaps in reperfusion times and in‐hospital outcomes between women and men. Methods 1928 patients (413 women, 21.4%) presented with an acute STEMI between June 2007 and March 2016. The population was divided into an early cohort (n = 728 patients, 2007‐May 2011), and a late cohort (n = 1200 patients, June 2011–2016). The primary endpoints evaluated were reperfusion times and in‐hospital outcomes. Results Compared to men, women experienced significant delays in first medical contact (FMC) to arrival at the emergency room (26.0 vs. 22.0 min, p 
ISSN:0160-9289
1932-8737
DOI:10.1002/clc.23658