A Case of Recurrent Painful Ophthalmoplegic Neuropathy Successfully Treated with Beta-blocker Eye Drop Instillation

Recurrent painful ophthalmoplegic neuropathy (RPON) is a rare disorder, which typically occurs in children, and causes headaches and unilateral oculomotor palsy. Early high-dose corticosteroid therapy is recommended to rapidly resolve acute episodes. However, the pathophysiology and therapeutic opti...

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Bibliographic Details
Published in:Neuro-ophthalmology (Amsterdam : Aeolus Press. 1980) 2021-09, Vol.45 (5), p.320-323
Main Authors: Takemoto, Daisuke, Ohkubo, Shinji, Udagawa, Sachiko, Kuroda, Mondo, Sugiyama, Kazuhisa
Format: Article
Language:English
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Case Report
Case Reports
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Summary:Recurrent painful ophthalmoplegic neuropathy (RPON) is a rare disorder, which typically occurs in children, and causes headaches and unilateral oculomotor palsy. Early high-dose corticosteroid therapy is recommended to rapidly resolve acute episodes. However, the pathophysiology and therapeutic options for this disorder remain to be fully elucidated. We report a case with typical clinical features of RPON successfully treated with beta-blocker eye drop instillation after the effects of high-dose corticosteroid and other therapies were not sufficient. We propose that beta-blocker eye drop instillation should be considered for patients with corticosteroid-resistant RPON.
ISSN:0165-8107
1744-506X
DOI:10.1080/01658107.2020.1791190