Self-collected mid-nasal swabs and saliva specimens, compared with nasopharyngeal swabs, for SARS-CoV-2 detection in mild COVID-19 patients

•Self-collected nasal and saliva samples can be used for SARS-CoV-2 screening.•Self-collected nasal and saliva specimens had a 99% and 90% sensitivity, respectively.•Nasopharyngeal swab viral loads correlate better with nasal than saliva.•Viral load correlations are poorer at day 7, when lower viral...

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Bibliographic Details
Published in:The Journal of infection 2021-12, Vol.83 (6), p.709-737
Main Authors: Alemany, Andrea, Millat-Martinez, Pere, Ouchi, Dan, Corbacho-Monné, Marc, Bordoy, Antoni E., Esteban, Cristina, Hernández, Águeda, Casañ, Cristina, Gonzalez, Victoria, Costes, Gèlia, Capdevila-Jáuregui, Mar, Torrano-Soler, Pamela, San José, Alba, Ara, Jordi, Prat, Núria, Clotet, Bonaventura, Bassat, Quique, Gimenez, Montserrat, Blanco, Ignacio, Baro, Bàrbara, Mitjà, Oriol
Format: Article
Language:English
Subjects:
COVID-19
Diagnostic Tests, Routine
Humans
Letter to the Editor
Nasal
Nasopharyngeal swab
Nasopharynx
RNA, Viral
Saliva
SARS-CoV-2
Screening
Specimen Handling
Viral load
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Description
Summary:•Self-collected nasal and saliva samples can be used for SARS-CoV-2 screening.•Self-collected nasal and saliva specimens had a 99% and 90% sensitivity, respectively.•Nasopharyngeal swab viral loads correlate better with nasal than saliva.•Viral load correlations are poorer at day 7, when lower viral loads are observed.
ISSN:0163-4453
1532-2742
DOI:10.1016/j.jinf.2021.09.012