Changes in characteristics and outcomes of critically ill COVID-19 patients in Tyrol (Austria) over 1 year

Summary Background Widely varying mortality rates of critically ill Coronavirus disease 19 (COVID-19) patients in the world highlighted the need for local surveillance of baseline characteristics, treatment strategies and outcome. We compared two periods of the COVID-19 pandemic to identify importan...

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Published in:Wiener Klinische Wochenschrift 2021-12, Vol.133 (23-24), p.1237-1247
Main Authors: Mayerhöfer, Timo, Klein, Sebastian J., Peer, Andreas, Perschinka, Fabian, Lehner, Georg F., Hasslacher, Julia, Bellmann, Romuald, Gasteiger, Lukas, Mittermayr, Markus, Eschertzhuber, Stephan, Mathis, Simon, Fiala, Anna, Fries, Dietmar, Kalenka, Armin, Foidl, Eva, Hasibeder, Walter, Helbok, Raimund, Kirchmair, Lukas, Stögermüller, Birgit, Krismer, Christoph, Heiner, Tatjana, Ladner, Eugen, Thomé, Claudius, Preuß-Hernandez, Christian, Mayr, Andreas, Pechlaner, Agnes, Potocnik, Miriam, Reitter, Bruno, Brunner, Jürgen, Zagitzer-Hofer, Stefanie, Ribitsch, Alexandra, Joannidis, Michael
Format: Article
Language:English
Subjects:
Aged
Austria
COVID-19
Critical Illness
Endocrinology
Gastroenterology
Humans
Intensive Care Units
Internal Medicine
Medicine
Medicine & Public Health
Middle Aged
Original
Original Article
Pandemics
Pneumology/Respiratory System
Respiration, Artificial
Retrospective Studies
SARS-CoV-2
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Summary:Summary Background Widely varying mortality rates of critically ill Coronavirus disease 19 (COVID-19) patients in the world highlighted the need for local surveillance of baseline characteristics, treatment strategies and outcome. We compared two periods of the COVID-19 pandemic to identify important differences in characteristics and therapeutic measures and their influence on the outcome of critically ill COVID-19 patients. Methods This multicenter prospective register study included all patients with a SARS-CoV‑2 infection confirmed by polymerase chain reaction, who were treated in 1 of the 12 intensive care units (ICU) from 8 hospitals in Tyrol, Austria during 2 defined periods (1 February 2020 until 17 July: first wave and 18 July 2020 until 22 February 2021: second wave) of the COVID-19 pandemic. Results Overall, 508 patients were analyzed. The majority ( n  = 401) presented during the second wave, where the median age was significantly higher (64 years, IQR 54–74 years vs. 72 years, IQR 62–78 years, p  
ISSN:0043-5325
1613-7671
DOI:10.1007/s00508-021-01945-5