SARS-CoV-2 IgG antibody responses in rt-PCR-positive cases: first report from India

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody responses remain poorly understood and the clinical utility of serological testing is still unclear. To understand the relationship between the antibody response to SARS-CoV-2 infection and the demographics and cycle threshold ( )...

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Published in:Access microbiology 2021, Vol.3 (10), p.000267-000267
Main Authors: Dash, Girish Chandra, Parai, Debaprasad, Choudhary, Hari Ram, Peter, Annalisha, Rout, Usha Kiran, Nanda, Rashmi Ranjan, Kshatri, Jaya Singh, Kanungo, Srikanta, Palo, Subrata Kumar, Mandal, Nityananda, Pati, Sanghamitra, Bhattacharya, Debdutta
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creator Dash, Girish Chandra
Parai, Debaprasad
Choudhary, Hari Ram
Peter, Annalisha
Rout, Usha Kiran
Nanda, Rashmi Ranjan
Kshatri, Jaya Singh
Kanungo, Srikanta
Palo, Subrata Kumar
Mandal, Nityananda
Pati, Sanghamitra
Bhattacharya, Debdutta
description Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody responses remain poorly understood and the clinical utility of serological testing is still unclear. To understand the relationship between the antibody response to SARS-CoV-2 infection and the demographics and cycle threshold ( ) values of confirmed RT-PCR patients. A total of 384 serum samples were collected from individuals between 4-6 weeks after confirmed SARS-CoV-2 infection and tested for the development of immunoglobulin class G (IgG) against SARS-CoV-2. The values, age, gender and symptoms of the patients were correlated with the development of antibodies. IgG positivity was found to be 80.2 % (95 % CI, 76.2-84.2). Positivity increased with a decrease in the value, with the highest (87.6 %) positivity observed in individuals with values
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title SARS-CoV-2 IgG antibody responses in rt-PCR-positive cases: first report from India
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