Effects of different types of tooth movement and force magnitudes on the amount of tooth movement and root resorption in rats

• Published in: The Angle orthodontist 2014-11, Vol.84 (6), p.1079-1085
• Main Authors: Nakano, Takako, Hotokezaka, Hitoshi, Hashimoto, Megumi, Sirisoontorn, Irin, Arita, Kotaro, Kurohama, Takeshi, Darendeliler, M Ali, Yoshida, Noriaki
• Format: Article
• Language: English
• Subjects: Animals; Dental Alloys - chemistry; Female; Imaging, Three-Dimensional - methods; Maxilla; Microscopy, Confocal; Microscopy, Electron, Scanning; Molar - pathology; Nickel - chemistry; Original; Orthodontic Anchorage Procedures - instrumentation; Orthodontic Appliance Design; Orthodontic Wires; Rats; Rats, Wistar; Root Resorption - etiology; Stress, Mechanical; Titanium - chemistry; Tooth Crown - pathology; Tooth Movement Techniques - adverse effects; Tooth Movement Techniques - classification; Tooth Root - pathology; X-Ray Microtomography - methods
• ISSN: 0003-3219; 1945-7103
• DOI: 10.2319/121913-929.1

To investigate differences in the amount of tooth movement and root resorption that occurred after tipping and bodily movement of the maxillary first molar in rats. Ten-week-old female Wistar rats were divided into two groups according to type of tooth movement and subdivided into four subgroups according to the magnitude of applied force. Nickel-titanium closed-coil springs exerting forces of 10, 25, 50, or 100 g were applied to the maxillary left first molars to induce mesial tooth movement. We designed a novel orthodontic appliance for bodily tooth movement. Tooth movement distance and root resorption were measured using microcomputed tomography and scanning electron and scanning laser microscopy. The amount of tooth movement in the bodily tooth movement group was less than half that in the tipping tooth movement group. The greatest amount of tooth movement occurred in the 10-g tipping and 50-g bodily tooth movement subgroups, and the amount of tooth movement decreased with the application of an excessive magnitude of force. Conversely, root resorption increased when the heavier orthodontic force was applied in both groups. Root resorption in the tipping tooth movement group was approximately twice that in the bodily tooth movement group. Root resorption in the tipping tooth movement group was more pronounced than that in the bodily tooth movement group. Although the amount of tooth movement decreased when extremely heavy forces were applied, root resorption increased in both the tipping and bodily tooth movement groups in rats.